5-甲基-6H-吡啶并[4,3-b]咔唑合成路线 （共 13 条）
反应条件
sodium tetrahydroborate in ethanol
Heating;
参考文献
Modi, Sandeep P.; Carey, James J.; Archer, Sydney
Tetrahedron Letters, 1990 , vol. 31, # 41 p. 5845 - 5848
反应条件
sodium tetrahydroborate in ethanol
Heating;
参考文献
Modi, Sandeep P.; Carey, James J.; Archer, Sydney
Tetrahedron Letters, 1990 , vol. 31, # 41 p. 5845 - 5848
参考文献
Kano, Shinzo; Sugino, Eiichi; Shibuya, Shiroshi; Hibino, Satoshi
Journal of Organic Chemistry, 1981 , vol. 46, # 14 p. 2979 - 2981
反应条件
T=490 - 500°C; 0.05 h;
参考文献
Hibino; Sugino
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1751 - 1755
反应条件
T=450 - 460°C; 0.05 h;
参考文献
Hibino; Sugino
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1751 - 1755
反应条件
1: 68 percent / potassium hydride, HMPA / tetrahydrofuran / 20 h / Ambient temperature
2: 1.) tert-butyllithium / 1.) THF, r.t., 2 h; 2.) r.t., overnight
3: 72 percent / sodium hydroxide / methanol / 4 h / Heating
4: 89 percent / ethyl acetate / 5 h / 50 °C
6: 54 percent / triphenylphosphine / dimethylformamide / 86 h / Heating
View Scheme
参考文献
Kutney; Noda; Lewis; et al.
Canadian Journal of Chemistry, 1982 , vol. 60, # 19 p. 2426 - 2430
反应条件
1: 1.) tert-butyllithium / 1.) THF, r.t., 2 h; 2.) r.t., overnight
2: 72 percent / sodium hydroxide / methanol / 4 h / Heating
3: 89 percent / ethyl acetate / 5 h / 50 °C
5: 54 percent / triphenylphosphine / dimethylformamide / 86 h / Heating
View Scheme
参考文献
Kutney; Noda; Lewis; et al.
Canadian Journal of Chemistry, 1982 , vol. 60, # 19 p. 2426 - 2430
反应条件
1: 72 percent / sodium hydroxide / methanol / 4 h / Heating
2: 89 percent / ethyl acetate / 5 h / 50 °C
4: 54 percent / triphenylphosphine / dimethylformamide / 86 h / Heating
View Scheme
参考文献
Kutney; Noda; Lewis; et al.
Canadian Journal of Chemistry, 1982 , vol. 60, # 19 p. 2426 - 2430
反应条件
sodium tetrahydroborate; palladium on activated charcoal; trichlorophosphate
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Kutney, James P.; Noda, Masaki; Lewis, Norman G.; Monteiro, Beatrice; Mostowicz, Danuta; Worth, Brian R.
Heterocycles, 1981 , vol. 16, # 9 p. 1469 - 1472
参考文献
Kano, Shinzo; Sugino, Eiichi; Hibino, Satoshi
Heterocycles, 1982 , vol. 19, # 9 p. 1673 - 1676
