6-氨基-9H-嘌呤-9-丙酸合成路线 （共 5 条）
反应条件
hydrogenchloride in water
4 h; Inert atmosphereReflux;
参考文献
Dubois, Lilian; Acher, Francinec.; McCort-Tranchepain, Isabelle
Synlett, 2012 , vol. 23, # 5 p. 791 - 795
反应条件
1: 61 percent / K2CO3 / dimethylformamide / 24 h / 70 °C
2: aq. NaOH / ethanol / 20 °C
View Scheme
参考文献
Keuser; Pindur, Ulf
Pharmazie, 2006 , vol. 61, # 4 p. 261 - 268
反应条件
trifluoroacetic acid in dichloromethane
T=20°C; 2 h; Inert atmosphere;
参考文献
Dubois, Lilian; Acher, Francinec.; McCort-Tranchepain, Isabelle
Synlett, 2012 , vol. 23, # 5 p. 791 - 795
反应条件
hydrogenchloride; water
3 h; Reflux;
参考文献
Zhang, Yang-Ming; Ding, Yu; Tang, Wei; Luo, Wei; Gu, Min; Lu, Wei; Tang, Jie; Zuo, Jian-Ping; Nan, Fa-Jun
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 20 p. 9212 - 9216
反应条件
1,4-diaza-bicyclo[2.2.2]octane; tetrabutylammomium bromide
Michael addition; 0.133333 h; IrradiationInert atmosphereneat (no solvent); regioselective reaction;
参考文献
Dubois, Lilian; Acher, Francinec.; McCort-Tranchepain, Isabelle
Synlett, 2012 , vol. 23, # 5 p. 791 - 795
