5-羟基-2-硝基苯甲醛合成路线 （共 59 条）
反应条件
sodium tetrahydroborate in methanol T=0 - 20°C;
参考文献
Wong, Chi-Huey; Burton, Dennis R.; Wilson, Ian A.
Patent: US2007/213278 A1, 2007 ;
Location in patent: Page/Page column 29; Sheet 9 ;
反应条件
1: diluted alkaline solution / 60 °C 2: permanganate 3: tin (II)-chloride; concentrated hydrochloric acid View Scheme
参考文献
Heilbron et al.
Journal of the Chemical Society, 1925 , vol. 127, p. 2171
反应条件
piperidine; pyridine
参考文献
Chakravarti; Ganapati; Aravamudhachari
Journal of the Chemical Society, 1938 , p. 171
反应条件
sodium dithionite; water Diazotieren in bromwasserstoffsaurer Loesung und nachfolgende Behandlung mit Kupfer(I)-bromid;
参考文献
Hodgson; Beard
Journal of the Chemical Society, 1925 , vol. 127, p. 876,877
Journal of the Chemical Society, 1926 , p. 150
反应条件
potassium carbonate in DMF (N,N-dimethyl-formamide) T=20°C; 16 h;
参考文献
Ramurthy, Savithri; Costales, Abran; Jansen, Johanna M.; Levine, Barry; Renhowe, Paul A.; Shafer, Cynthia M.; Subramanian, Sharadha
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 4 p. 1678 - 1681
反应条件
sodium hydroxide in water T=40°C; pH=9 - 10; 5 h;
参考文献
Xiong, Xiao-Dong; Chen, Wen-Xue; Kuang, Yun-Yan; Chen, Fen-Er
Organic Preparations and Procedures International, 2009 , vol. 41, # 5 p. 423 - 427
反应条件
potassium carbonate in ethyl acetate; N,N-dimethyl-formamide
参考文献
Caldwell, Richard D.; GUCKIAN, Kevin M.; KUMARA VEL, Gnanasambandam; LEE, Wen-Cherng; LIN, Edward Yin-Shiang; LlU, Xiaogao; MA, Bin; SCOTT, Daniel M.; SHl, Zhan; THOMAS, Jermaine; TAVERAS, Arthur G.; ZHENG, Guo Zhu
Patent: US2014/100195 A1, 2014 ;
Location in patent: Page/Page column ;
参考文献
Tiemann; Ludwig
Chemische Berichte, 1882 , vol. 15, p. 2055
反应条件
1: 96 percent / Cs2CO3 / dimethylformamide / 15 h / 20 °C 2: 88 percent / NH2OH*HCl; MgSO4; p-TsOH*H2O / toluene / 15 h / Heating 3: 56 percent / SnCl2*H2O / methanol / 3 h / 70 °C View Scheme
参考文献
Manetsch, Roman; Zheng, Lei; Reymond, Martine T.; Woggon, Wolf-Dietrich; Reymond, Jean-Louis
Chemistry - A European Journal, 2004 , vol. 10, # 10 p. 2487 - 2506
反应条件
potassium carbonate in acetonitrile 16 h; Heating;
参考文献
Ruhland; Kuenzer
Tetrahedron Letters, 1996 , vol. 37, # 16 p. 2757 - 2760
