反应条件
1: 68 percent / HCOOH / methanol; H2O / 21 h / 20 °C 2: 100 percent / K2CO3 / tetrahydrofuran / 12 h / Heating 3: 1.) LiN(Si(CH3)3)2 / 1.) THF, -78 deg C, 1 h, 2.) -78 deg C, 15 min 4: 70 percent / LiOH, H2O2 / tetrahydrofuran; H2O / 15 h / 20 °C 5: 1.) DCC, 2.) DMAP / 1.) toluene, 20 deg C, 5 min, 2.) 20 deg C, 20 h 6: 1.) Zn-Cu, 2.) H2 / 2.) Pd / 1.) CH3COOH, CH3OH, 65 deg C, 30 min, 2.) CH3COOH, 40 deg C, 6 h View Scheme
参考文献
Kanazawa; Denis; Greene
Journal of Organic Chemistry, 1994 , vol. 59, # 6 p. 1238 - 1240
