1: 80 percent / formic acid / methanol; H2O / 23 h / 48 °C
2: 100 percent / potassium carbonate; sodium sulfate / tetrahydrofuran / 15 h / Heating
3: 95 percent / chiral thiourea derivative catalyst / toluene / 48 h / -40 °C
4: 99 percent / methanol / 12 h
View Scheme
参考文献
Wang, Qinggang; Leutzsch, Markus; Van Gemmeren, Manuel; List, Benjamin
Journal of the American Chemical Society, 2013 , vol. 135, # 41 p. 15334 - 15337
Wang, Qinggang; Leutzsch, Markus; Van Gemmeren, Manuel; List, Benjamin
Journal of the American Chemical Society, 2013 , vol. 135, # 41 p. 15334 - 15337
1: With formic acid; benzenesulphinic acid sodium salt in methanol; water
T=25°C; Inert atmosphere;
2: With potassium carbonate in tetrahydrofuran
12 h; Inert atmosphereReflux;