n-butyllithium in ethylene glycol dimethyl ether soln of LiCp and EtOtf stirred under N2 at 0°C, then for 1 h at room temp. and recooled to 0°C, treated with n-BuLi in hexane, after 2 h ZrCl4 in glyme was added, stirred overnight; filtered, evapd. to dryness under vac., recrystd. from hot hexane; elem. anal.;
参考文献
Newmark, Richard A.; Boardman, Larry D.; Siedle, Allen R.
Inorganic Chemistry, 1991 , vol. 30, p. 853 - 856
Booth, Brian L.; Haszeldine, Robert N.; Laali, Khosrow
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2887 - 2893
1: 2,4-diamino-6-hydroxypyrimidine With sodium hydride in N,N-dimethyl-formamide; mineral oil 0.5 h; Inert atmosphere; 2: ethyl trifluoromethanesulphonate in N,N-dimethyl-formamide; mineral oil
参考文献
BAYER HEALTHCARE AG
Patent: US2010/35902 A1, 2010 ;
Location in patent: Page/Page column 20 ;
