425379-21-1合成路线

参考文献

CONCERT PHARMACEUTICALS, INC.; HARBESON, Scott, L.; TUNG, Roger, D.; LIU, Julie, F.
Patent: WO2011/11712 A1, 2011 ;
Location in patent: Page/Page column 34-35 ;
WO 2011/011712 A1

862423-48-1

425379-21-1

参考文献

Gauthier Jr., Donald R.; Limanto, John; Devine, Paul N.; Desmond, Richard A.; Szumigala Jr., Ronald H.; Foster, Bruce S.; Volante
Journal of Organic Chemistry, 2005 , vol. 70, # 15 p. 5938 - 5945

1435-53-62,4-二溴-1-氟苯+

425379-16-42-溴-3-氟苯腈

425379-21-1

参考文献

Gauthier Jr., Donald R.; Limanto, John; Devine, Paul N.; Desmond, Richard A.; Szumigala Jr., Ronald H.; Foster, Bruce S.; Volante
Journal of Organic Chemistry, 2005 , vol. 70, # 15 p. 5938 - 5945

425379-18-6

425379-21-1

参考文献

Goodacre, Simon C.; Street, Leslie J.; Hallett, David J.; Crawforth, James M.; Kelly, Sarah; Owens, Andrew P.; Blackaby, Wesley P.; Lewis, Richard T.; Stanley, Joanna; Smith, Alison J.; Ferris, Pushpinder; Sohal, Bindi; Cook, Susan M.; Pike, Andrew; Brown, Nicola; Wafford, Keith A.; Marshall, George; Castro, Jose L.; Atack, John R.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 1 p. 35 - 38

425379-16-42-溴-3-氟苯腈

425379-21-1

参考文献

Russell, Michael G. N.; Carling, Robert W.; Street, Leslie J.; Hallett, David J.; Goodacre, Simon; Mezzogori, Elena; Reader, Michael; Cook, Susan M.; Bromidge, Frances A.; Newman, Robert; Smith, Alison J.; Wafford, Keith A.; Marshall, George R.; Reynolds, David S.; Dias, Rebecca; Ferris, Pushpindar; Stanley, Jo; Lincoln, Rachael; Tye, Spencer J.; Sheppard, Wayne F. A.; Sohal, Bindi; Pike, Andrew; Dominguez, Maria; Atack, John R.; Castro, Jose L.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 4 p. 1235 - 1238

403-54-33-氟苯腈

425379-21-1

参考文献

Gauthier Jr., Donald R.; Limanto, John; Devine, Paul N.; Desmond, Richard A.; Szumigala Jr., Ronald H.; Foster, Bruce S.; Volante
Journal of Organic Chemistry, 2005 , vol. 70, # 15 p. 5938 - 5945

656235-44-82-氰基-6-氟苯硼酸

425379-21-1

参考文献

Gauthier Jr., Donald R.; Limanto, John; Devine, Paul N.; Desmond, Richard A.; Szumigala Jr., Ronald H.; Foster, Bruce S.; Volante
Journal of Organic Chemistry, 2005 , vol. 70, # 15 p. 5938 - 5945

425379-17-5

425379-21-1

参考文献

Russell, Michael G. N.; Carling, Robert W.; Street, Leslie J.; Hallett, David J.; Goodacre, Simon; Mezzogori, Elena; Reader, Michael; Cook, Susan M.; Bromidge, Frances A.; Newman, Robert; Smith, Alison J.; Wafford, Keith A.; Marshall, George R.; Reynolds, David S.; Dias, Rebecca; Ferris, Pushpindar; Stanley, Jo; Lincoln, Rachael; Tye, Spencer J.; Sheppard, Wayne F. A.; Sohal, Bindi; Pike, Andrew; Dominguez, Maria; Atack, John R.; Castro, Jose L.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 4 p. 1235 - 1238

701-45-13-溴-4-氟硝基苯

425379-21-1

参考文献

Russell, Michael G. N.; Carling, Robert W.; Street, Leslie J.; Hallett, David J.; Goodacre, Simon; Mezzogori, Elena; Reader, Michael; Cook, Susan M.; Bromidge, Frances A.; Newman, Robert; Smith, Alison J.; Wafford, Keith A.; Marshall, George R.; Reynolds, David S.; Dias, Rebecca; Ferris, Pushpindar; Stanley, Jo; Lincoln, Rachael; Tye, Spencer J.; Sheppard, Wayne F. A.; Sohal, Bindi; Pike, Andrew; Dominguez, Maria; Atack, John R.; Castro, Jose L.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 4 p. 1235 - 1238

425378-68-32-氟-5-硝基苯基硼酸频那醇酯

425379-21-1

参考文献

Goodacre, Simon C.; Street, Leslie J.; Hallett, David J.; Crawforth, James M.; Kelly, Sarah; Owens, Andrew P.; Blackaby, Wesley P.; Lewis, Richard T.; Stanley, Joanna; Smith, Alison J.; Ferris, Pushpinder; Sohal, Bindi; Cook, Susan M.; Pike, Andrew; Brown, Nicola; Wafford, Keith A.; Marshall, George; Castro, Jose L.; Atack, John R.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 1 p. 35 - 38