3-(S)-氨基-2-哌啶酮盐酸盐合成路线 （共 7 条）
反应条件
hydrogenchloride in ethyl acetate T=0°C; 1 h;
参考文献
Yu, Kuo-Long; Rajakumar, G.; Srivastava, Lalit K.; Mishra, Ram K.; Johnson, Rodney L.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 7 p. 1430 - 1436
反应条件
sodium methylate in methanol
参考文献
Miyamura, Kazuo; Hata, Kazuhiko; Makino, Tadashi; Saburi, Masahiko; Yoshikawa, Sadao
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1987 , p. 1127 - 1132
反应条件
1: AcOH, H2 / Pd/C / methanol / 1 h / 2068.6 Torr 2: Na2CO3 / dimethylformamide / 48 h 3: 99 percent / HCl / ethyl acetate / 1 h / 0 °C View Scheme
参考文献
Yu, Kuo-Long; Rajakumar, G.; Srivastava, Lalit K.; Mishra, Ram K.; Johnson, Rodney L.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 7 p. 1430 - 1436
反应条件
1: SOCl2 / -15 - 20 °C 2: 2.25 mg / Et3N / acetonitrile / 4 h / 20 °C View Scheme
参考文献
Abe, Masatoshi; Nagai, Masashi; Yamamoto, Keiichiro; Yamazaki, Hiroko; Koga, Ichiro; Satoh, Yoshitaka; Muraoka, Yasuhiko; Kurashige, Shuji; Ichikawa, Yuh-Ichiro
Organic Process Research and Development, 2005 , vol. 9, # 5 p. 570 - 576
反应条件
1: Na2CO3 / dimethylformamide / 48 h 2: 99 percent / HCl / ethyl acetate / 1 h / 0 °C View Scheme
参考文献
Yu, Kuo-Long; Rajakumar, G.; Srivastava, Lalit K.; Mishra, Ram K.; Johnson, Rodney L.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 7 p. 1430 - 1436
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 24 h; Heating;
参考文献
Miyamura, Kazuo; Hata, Kazuhiko; Makino, Tadashi; Saburi, Masahiko; Yoshikawa, Sadao
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1987 , p. 1127 - 1132
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 24 h; Heating;
参考文献
Miyamura, Kazuo; Hata, Kazuhiko; Makino, Tadashi; Saburi, Masahiko; Yoshikawa, Sadao
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1987 , p. 1127 - 1132
