2-溴-5-氯噻唑-4-羧酸乙酯合成路线 （共 4 条）
反应条件
1: With tert.-butylnitrite in acetonitrile T=60 - 80°C; 2 h; 2: With hydrogenchloride in dichloromethane; acetonitrile
参考文献
Hodgetts, Kevin J.; Kershaw, Mark T.
Organic Letters, 2002 , vol. 4, # 8 p. 1363 - 1365
反应条件
1: N-chlorosuccinimide / acetonitrile / 20 °C 2: 30 g / isoamylnitrite; CuBr2 / acetonitrile / 2 h / 0 °C View Scheme
参考文献
Hodgetts, Kevin J.; Kershaw, Mark T.
Organic Letters, 2002 , vol. 4, # 8 p. 1363 - 1365
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in toluene T=80°C; Suzuki coupling; 4 h;
参考文献
Hodgetts, Kevin J.; Kershaw, Mark T.
Organic Letters, 2002 , vol. 4, # 8 p. 1363 - 1365
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in toluene
T=80°C; Suzuki coupling; 4 h;
参考文献
Hodgetts, Kevin J.; Kershaw, Mark T.
Organic Letters, 2002 , vol. 4, # 8 p. 1363 - 1365
