1,2-双(4-氯苯基)-2-羟基乙酮合成路线 （共 62 条）
反应条件
1: 4-chlorobenzaldehyde With potassium tert-butylate; [mmim][I] in tetrahydrofuran
T=20°C; 3 h;
2: acrylic acid methyl ester in tetrahydrofuran
T=20°C; 8 h;
参考文献
Ye, Wei; Cai, Guanliang; Zhuang, Zeyang; Jia, Xueshun; Zhai, Hongbin
Organic Letters, 2005 , vol. 7, # 17 p. 3769 - 3771
反应条件
triethylamine; 5-(2-hydroxyethyl)-4-methyl-3-(phenylmethyl)thiazolium chloride in various solvent(s)
T=80°C; Stetter reaction; 12 h;
参考文献
Anjaiah, Siddam; Chandrasekhar, Srivari; Gree, Rene
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 11 p. 1329 - 1334
反应条件
N-hexadecyl-N,N,N-trimethylammonium bromide
T=30°C; 24 h; pH 8.0 with 0.05 M phosphate; Mechanism;
参考文献
Shinkai, Seiji; Yamashita, Takaharu; Kusano, Yumiko; Manabe, Osamu
Tetrahedron Letters, 1980 , vol. 21, p. 2543 - 2546
反应条件
potassium phosphate; (S)-5-benzyl-2-(2,6-dimethoxyphenyl)-6,6-dimethyl-6,8-dihydro-5H-[1,2,4]triazolo[3,4-c][1,4]oxazin-2-ium tetrafluoroborate in 1,4-dioxane
T=40°C; 0.166667 h; Inert atmosphere;
参考文献
Liu, Fan; Bugaut, Xavier; Schedler, Michael; Froehlich, Roland; Glorius, Frank
Angewandte Chemie - International Edition, 2011 , vol. 50, # 52 p. 12626 - 12630
反应条件
2-pentafluorophenyl-6,17dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; caesium carbonate in m-xylene
T=20°C; Inert atmosphere; Solvent; chemoselective reaction;
参考文献
Jin, Ming Yu; Kim, Sun Min; Mao, Hui; Ryu, Do Hyun; Song, Choong Eui; Yang, Jung Woon
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 10 p. 1547 - 1550
反应条件
tris(trifluoroacetoxy)-λ3-iodane in tetrachloromethane
T=23°C; 3 h;
参考文献
Futami; Nishino; Kurosawa
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 10 p. 3182 - 3186
反应条件
potassium phosphate; (S)-5-benzyl-2-(2,6-dimethoxyphenyl)-6,6-dimethyl-6,8-dihydro-5H-[1,2,4]triazolo[3,4-c][1,4]oxazin-2-ium tetrafluoroborate in 1,4-dioxane
T=40°C; 6 h; Inert atmosphere;
参考文献
Liu, Fan; Bugaut, Xavier; Schedler, Michael; Froehlich, Roland; Glorius, Frank
Angewandte Chemie - International Edition, 2011 , vol. 50, # 52 p. 12626 - 12630
反应条件
cadmium(II) sulphide in acetonitrile
T=20°C; P=37.5038 Torr; 24 h; Inert atmosphereIrradiation;
参考文献
Mitkina, Tatiana; Stanglmair, Christoph; Setzer, Wolfgang; Gruber, Michael; Kisch, Horst; Koenig, Burkhard
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 17 p. 3556 - 3561
反应条件
3-(2,4,6-trimethyl-phenyl)-5,6,7,8-tetrahydro-4H-cycloheptathiazol-3-ium perchlorate; potassium tert-butylate in 1,4-dioxane
T=30 - 70°C; Stetter reaction; 2.75 h; Inert atmosphere;
参考文献
Bhunia, Anup; Yetra, Santhivardhana Reddy; Bhojgude, Sachin Suresh; Biju, Akkattu T.
Organic Letters, 2012 , vol. 14, # 11 p. 2830 - 2833
反应条件
3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; caesium carbonate in tetrahydrofuran
T=20°C; Inert atmosphere; chemoselective reaction;
参考文献
Jin, Ming Yu; Kim, Sun Min; Mao, Hui; Ryu, Do Hyun; Song, Choong Eui; Yang, Jung Woon
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 10 p. 1547 - 1550
