2,3-二氢-1H-茚-2-羧酸甲酯合成路线 （共 16 条）
反应条件
1: KOH / H2O / 16 h / Heating
2: 0.33 h / 200 °C
3: 94 percent / conc. H2SO4 / 1 h / Heating
View Scheme
参考文献
Tomiyama; Wakabayashi; Yokota
Journal of Medicinal Chemistry, 1989 , vol. 32, # 8 p. 1988 - 1996
反应条件
1: Na / ethanol; diethyl ether / 5 h / Heating
2: KOH / H2O / 16 h / Heating
3: 0.33 h / 200 °C
4: 94 percent / conc. H2SO4 / 1 h / Heating
View Scheme
参考文献
Tomiyama; Wakabayashi; Yokota
Journal of Medicinal Chemistry, 1989 , vol. 32, # 8 p. 1988 - 1996
反应条件
1: 0.33 h / 200 °C
2: 94 percent / conc. H2SO4 / 1 h / Heating
View Scheme
参考文献
Tomiyama; Wakabayashi; Yokota
Journal of Medicinal Chemistry, 1989 , vol. 32, # 8 p. 1988 - 1996
参考文献
Mousseron; Nguyen Phuoc Du
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1944 , vol. 218, p. 281
反应条件
anschliessendes Erwaermen mit Methanol;
参考文献
Treibs
Chemische Berichte, 1959 , vol. 92, p. 2152,2159
反应条件
1: With lithium diisopropyl amide in tetrahydrofuran
T=-5 - 0°C; Inert atmosphere;
2: With hydrogenchloride in tetrahydrofuran; water
pH=ca. 4;
参考文献
Maloney, Kevin M.; Chung, John Y. L.
Journal of Organic Chemistry, 2009 , vol. 74, # 19 p. 7574 - 7576
