2-(4-甲氧苯基)噻吩合成路线 （共 72 条）
反应条件
potassium carbonate; [PS-PEG-adppp-Pd(η3-C3H5)]Cl in water T=50°C; Suzuki-Miyaura coupling; 12 h;
参考文献
Uozumi, Yasuhiro; Nakai, Yasushi
Organic Letters, 2002 , vol. 4, # 17 p. 2997 - 3000
反应条件
1: thiophene With n-butyllithium; magnesium bromide in tetrahydrofuran T=20°C; 2 h; 2: 1-bromo-4-methoxy-benzene With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in tetrahydrofuran 18 h; Heating;
参考文献
Bayh, Omar; Awad, Hacan; Mongin, Florence; Hoarau, Christophe; Trecourt, Francois; Queguiner, Guy; Marsais, Francis; Blanco, Fernando; Abarca, Belen; Ballesteros, Rafael
Tetrahedron, 2005 , vol. 61, # 20 p. 4779 - 4784
反应条件
potassium carbonate; [PS-PEG-adppp-Pd(η3-C3H5)]Cl in water T=50°C; Suzuki-Miyaura coupling; 12 h;
参考文献
Uozumi, Yasuhiro; Nakai, Yasushi
Organic Letters, 2002 , vol. 4, # 17 p. 2997 - 3000
反应条件
potassium phosphate; tetrabutylammomium bromide; palladium diacetate in ethanol T=20°C; Suzuki cross-coupling reaction; 3 h;
参考文献
Deng, Yijian; Gong, Liuzhu; Mi, Aiqiao; Liu, Hui; Jiang, Yaozhong
Synthesis, 2003 , # 3 p. 337 - 339
反应条件
tris-(dibenzylideneacetone)dipalladium(0); N,N,N',N,-tetramethylethylenediamine; tri-tert-butyl phosphine in tetrahydrofuran; toluene T=40°C; 1 h; Schlenk techniqueInert atmosphere;
参考文献
Giannerini, Massimo; Fananas-Mastral, Martin; Feringa, Ben L.
Nature Chemistry, 2013 , vol. 5, # 8 p. 667 - 672
反应条件
bis(η3-allyl-μ-chloropalladium(II)); triphenyl-arsane; caesium carbonate in 1,4-dioxane; water T=90°C; 24 h; Inert atmosphere;
参考文献
Fuse, Shinichiro; Yoshida, Hayato; Takahashi, Takashi
Tetrahedron Letters, 2012 , vol. 53, # 26 p. 3288 - 3291
反应条件
water; oxane palladiumgt;; silica-supported polylt;3-(2-cyanoethylsulfanyl)propylsil in acetonitrile T=80°C; 5 h;
参考文献
Kang, Suk-Ku; Baik, Tae-Gon; Song, Si-Young
Synlett, 1999 , # 3 p. 327 - 329
反应条件
sodium methylate; copper(l) iodide; Pd(dibenzylidene acetone)3*CHCl3 in methanol; acetonitrile T=60°C; 2 h;
参考文献
Kang, Suk-Ku; Ryu, Hyung-Chul; Choi, Sang-Chul
Chemical Communications, 1998 , # 12 p. 1317 - 1318
反应条件
caesium carbonate; palladium dichloride in acetonitrile T=20°C; Substitution; 3 h;
参考文献
Kang, Suk-Ku; Lee, Sang-Woo; Ryu, Hyung-Chul
Chemical Communications, 1999 , # 20 p. 2117 - 2118
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=120°C; Suzuki coupling; 18 h;
参考文献
Hebel, Andre; Haag, Rainer
Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9452 - 9455
