1.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine / acetonitrile / 16 h / 20 °C 2.1: trichlorophosphate / toluene / 16 h / |Reflux 2.2: 6 h / -78 °C 3.1: hydrogen; palladium(II) oxide hydrate / ethyl acetate; methanol; water / 23 h / 20 °C 4.1: ammonia; sodium / 1,4-dioxane / 2 h / -78 °C View Scheme

1.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine / acetonitrile / 16 h / 20 °C 2.1: trichlorophosphate / toluene / 16 h / |Reflux 2.2: 6 h / -78 °C 3.1: hydrogen; palladium(II) oxide hydrate / ethyl acetate; methanol; water / 23 h / 20 °C 4.1: ammonia; sodium / 1,4-dioxane / 2 h / -78 °C View Scheme

1.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine / acetonitrile / 16 h / 20 °C 2.1: trichlorophosphate / toluene / 16 h / |Reflux 2.2: 6 h / -78 °C 3.1: hydrogen; palladium(II) oxide hydrate / ethyl acetate; methanol; water / 23 h / 20 °C 4.1: ammonia; sodium / 1,4-dioxane / 2 h / -78 °C View Scheme