T=350°C;

T=350°C;

暂无反应条件数据

T=350°C;

2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene T=80°C; 8 h; Title compound not separated from byproducts;

1: 1) n-BuLi, N-isopropylcyclohexylamine / 1) THF, -70 deg C, 1 h, 2) THF, HMPA, r.t., overnight 2: 20percent aq. NaOH / methanol / 2 h / Heating 3: 1) diphenylphosphorazidate, Et3N, 2) 15percent HCl, AcOH / 1) benzene, a) 1 h, b) r.t., 1 h, c) reflux, 3 h, 2) r.t., overnight 4: 60 percent / SO2Cl2, Et3N / diethyl ether / a) -70 deg C, 2 h, b) -20 deg C, overnight 5: 1) NaH, 2) tert-butyl hypochlorite / 1) hexane, r.t., 3 h, 2) hexane, r.t., overnight 6: 43 percent / diethyl ether / 6 h / 23 °C / Irradiation; variation of concentration; addition of Ph2PH; addition of Mg-powder, activated by various methods View Scheme

1: 1) diphenylphosphorazidate, Et3N, 2) 15percent HCl, AcOH / 1) benzene, a) 1 h, b) r.t., 1 h, c) reflux, 3 h, 2) r.t., overnight 2: 60 percent / SO2Cl2, Et3N / diethyl ether / a) -70 deg C, 2 h, b) -20 deg C, overnight 3: 1) NaH, 2) tert-butyl hypochlorite / 1) hexane, r.t., 3 h, 2) hexane, r.t., overnight 4: 43 percent / diethyl ether / 6 h / 23 °C / Irradiation; variation of concentration; addition of Ph2PH; addition of Mg-powder, activated by various methods View Scheme

1: biphenyl With lithium in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere; 2: 6-fluoro-6-methyl-1-heptene in tetrahydrofuran T=0°C; 0.5 h; Inert atmosphere; regioselective reactionFurther stages;

benzophenone; ethylmagnesium bromide 1.) ether, 8 h, 2.) THF, 6 h; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;

1: 29 percent / SOCl2 / pyridine / -17 °C 2: 40 percent Chromat. / Bu3SnH, azobisisobutyronitrile (AIBN) / benzene / 8 h / 80 °C View Scheme