反-1-辛烯-1-基硼酸合成路线 （共 12 条）
反应条件
1: With Br2BH-SMe2 2: With sodium hydroxide
参考文献
Thadani, Avinash N.; Batey, Robert A.
Tetrahedron Letters, 2003 , vol. 44, # 44 p. 8051 - 8055
参考文献
Fairlamb, Ian J. S.; Marrison, Lester R.; Dickinson, Julia M.; Lu, Feng-Ju; Schmidt, Jan Peter
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 15 p. 4285 - 4299
反应条件
1: 1-propenylmagnesium bromide With boric acid trimethyl ester in tetrahydrofuran; diethyl ether T=-78°C; 1 h; 2: With hydrogenchloride 0.5 h; cooling; 3: oct-1-ene With Grubb's 2nd generation catalyst in dichloromethane olefin cross-metathesis; 12 h; Heating; Title compound not separated from byproducts;
参考文献
Morrill, Christie; Grubbs, Robert H.
Journal of Organic Chemistry, 2003 , vol. 68, # 15 p. 6031 - 6034
反应条件
1.1: -78 °C 2.1: KHF2 3.1: 68 percent / (n-Bu)4NI / CH2Cl2; H2O / 0.5 h / 20 °C 4.1: O3 / -78 °C 4.2: DMS / -78 - 20 °C 5.1: NaClO2; NaH2PO4*H2O; 2-methyl-2-butene 6.1: 89 percent / PhSO2Cl / 48 h / 4 °C 7.1: 98 percent / HF / acetonitrile View Scheme
参考文献
Thadani, Avinash N.; Batey, Robert A.
Tetrahedron Letters, 2003 , vol. 44, # 44 p. 8051 - 8055
反应条件
palladium diacetate; sodium acetate in acetic acid T=50°C; 20 h;
参考文献
Journal of Organometallic Chemistry, , vol. 465, # 1-2 p. 85 - 92
反应条件
palladium diacetate; sodium acetate in acetic acid T=50°C; 20 h;
参考文献
Journal of Organometallic Chemistry, , vol. 465, # 1-2 p. 85 - 92
反应条件
1.1: -78 °C 2.1: KHF2 3.1: 68 percent / (n-Bu)4NI / CH2Cl2; H2O / 0.5 h / 20 °C 4.1: O3 / -78 °C 4.2: DMS / -78 - 20 °C 5.1: NaClO2; NaH2PO4*H2O; 2-methyl-2-butene 6.1: 89 percent / PhSO2Cl / 48 h / 4 °C 7.1: 98 percent / HF / acetonitrile View Scheme
参考文献
Thadani, Avinash N.; Batey, Robert A.
Tetrahedron Letters, 2003 , vol. 44, # 44 p. 8051 - 8055
反应条件
palladium diacetate; sodium acetate in acetic acid
T=50°C; 20 h;
参考文献
Cho, Chan Sik; Uemura, Sakae
Journal of Organometallic Chemistry, 1994 , vol. 465, # 1-2 p. 85 - 92
反应条件
tetrakis(triphenylphosphine) palladium(0); cesium fluoride in benzene
T=70°C; 17 h; Inert atmosphere;
参考文献
Burks, Heather E.; Kliman, Laura T.; Morken, James P.
Journal of the American Chemical Society, 2009 , vol. 131, # 26 p. 9134 - 9135
反应条件
in pentane
under N2; to suspn. of boronic acid in pentane added i-PrOH in separatory funnel, shook for few s, H2O removed, i-PrOH added, shook for few s; H2O layer removed, org. layer dried with MgSO4, solvents evapd., distd.;
参考文献
Brown, Herbert C.; Bhat N. G.; Somayaji, Vishwanatha
Organometallics, 1983 , vol. 2, p. 1311 - 1316
