1: 6-bromo-2-(4-fluoropjhenyl)imidazo[1,2-a]pyridine With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: With zinc(II) chloride in tetrahydrofuran; hexane T=-78°C; 1 h; 3: iodobenzene With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; hexane Negishi-cross-coupling reaction; 16 h; Heating;

in toluene 5.5 h;

in ethanol 5 h; Heating;