1-Boc-4-烯丙基-4-哌啶甲酸合成路线 （共 4 条）
反应条件
1: With lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; 1 h; 2: With chloro-trimethyl-silane in tetrahydrofuran T=-78 - 20°C; 1 h; 3: With hydrogenchloride more than 3 stages;
参考文献
TORAY INDUSTRIES, INC.
Patent: EP2009006 A1, 2008 ;
Location in patent: Page/Page column 110 ;
反应条件
water; potassium hydroxide in tetrahydrofuran; methanol T=65°C; 5.5 h;
参考文献
Ferreira, Andrew J.; Solano, Danielle M.; Oakdale, James S.; Kurth, Mark J.
Synthesis, 2011 , # 20 art. no. M68111SS, p. 3241 - 3246
反应条件
potassium tert-butylate in tetrahydrofuran; water
参考文献
Baque, Eric; Carry, Jean-Christophe; El-Ahmad, Youssef; Evers, Michel; Hubert, Philippe; Malleron, Jean-Luc; Mignani, Serge; Pantel, Guy; Tabart, Michel; Viviani, Fabrice
Patent: US2002/111492 A1, 2002 ;
反应条件
1: LDA / tetrahydrofuran / -78 °C 2: KOH / methanol / Heating View Scheme
参考文献
Ferreira, Andrew J.; Solano, Danielle M.; Oakdale, James S.; Kurth, Mark J.
Synthesis, 2011 , # 20 art. no. M68111SS, p. 3241 - 3246
