5-二甲氨基-1-萘磺酸合成路线 （共 14 条）
反应条件
phosphorus pentachloride 2 h;
参考文献
Horner, L.; Lindel, H.
Phosphorus and Sulfur and the Related Elements, 1983 , vol. 15, p. 1 - 8
反应条件
1: PCl5 2: NH3 View Scheme
参考文献
Weber
Biochemical Journal, 1952 , vol. 51, p. 155,157, 158
反应条件
1: 75 percent / PCl3 / 2 h / 60 °C
2: 85 percent / Na2SO3, 40percent NaOH / H2O / 2.5 h / Ambient temperature
3: 65 percent / NaOH / H2O; ethanol / 20 h / 80 °C
View Scheme
参考文献
Horner, L.; Lindel, H.
Phosphorus and Sulfur and the Related Elements, 1983 , vol. 15, p. 1 - 8
反应条件
1: 80 percent / PCl5 / 2 h
2: 1.) Na2SO3, Na2CO3, 2.) Tetrabutylammonium bromide / 1.) 5 min, reflux, water, 2.) 24 h, reflux, 1,2-dimethoxyethane
3: 1.) Thionylchlorid, 2.) Triethylamin / 1.) room temperature, CHCl3, 2.) room temperature, 24 h, benzene
View Scheme
参考文献
Horner, L.; Lindel, H.
Phosphorus and Sulfur and the Related Elements, 1983 , vol. 15, p. 1 - 8
