4,6-二氯-1H-吡唑并[3,4-C]嘧啶合成路线 (共 17 条)
反应条件
1: aqueous KOH
2: ethanol; NH3 / 200 °C
3: pyridine; P2S5
View Scheme
参考文献
Robins
Journal of the American Chemical Society, 1957 , vol. 79, p. 6407,6412
参考文献
F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; FENG, Jianwen; HAYNES, Nancy-Ellen; HERMANN, Johannes Cornelius; KIM, Kyungjin; LIU, Jin-Jun; SCOTT, Nathan Robert; YI, Lin; ZAK, Mark; ZHAO, Guiling
Patent: WO2013/182546 A1, 2013 ;
Location in patent: Page/Page column 85; 86 ;
反应条件
1: NaHS; water
2: aq. NaOH solution
View Scheme
参考文献
Robins
Journal of the American Chemical Society, 1957 , vol. 79, p. 6407,6412
参考文献
Robins
Journal of the American Chemical Society, 1957 , vol. 79, p. 6407,6412
反应条件
1: methanol.KOH
2: aqueous KOH
3: H2O
View Scheme
参考文献
Robins
Journal of the American Chemical Society, 1957 , vol. 79, p. 6407,6412
参考文献
Robins
Journal of the American Chemical Society, 1957 , vol. 79, p. 6407,6412
参考文献
Robins
Journal of the American Chemical Society, 1957 , vol. 79, p. 6407,6412