乙基2-(3,4,5-三甲氧基苯基)吡啶-4-羧酸酯合成路线 （共 2 条）
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; toluene
T=90°C;
参考文献
Kowa Co., Ltd.
Patent: EP1568691 A1, 2005 ;
Location in patent: Page/Page column 14 ;
反应条件
1: 58 percent / DIBAL-H / 20 °C
2: 99 percent / thionyl chloride / benzene / 0.17 h / Heating
View Scheme
参考文献
Filosa, Rosanna; Peduto, Antonella; de Caprariis, Paolo; Saturnino, Carmela; Festa, Michela; Petrella, Antonello; Pau, Amedeo; Pinna, Gerard Aime; La Colla, Paolo; Busonera, Bernardetta; Loddo, Roberta
European Journal of Medicinal Chemistry, 2007 , vol. 42, # 3 p. 293 - 306
