2-(4-硝基苯基)吡啶合成路线 （共 46 条）
反应条件
copper(I) oxide; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; palladium dichloride in N,N-dimethyl acetamide T=150°C; 24 h; Inert atmosphereMolecular sieve;
参考文献
Li, Xinjian; Zou, Dapeng; Leng, Faqiang; Sun, Chunxia; Li, Jingya; Wu, Yangjie; Wu, Yusheng
Chemical Communications, 2013 , vol. 49, # 3 p. 312 - 314
反应条件
tetrakis(triphenylphosphine) palladium(0); hexamethyl-distannane; lithium chloride in 1,4-dioxane Heating;
参考文献
Hitchcock; Mayhugh; Gregory
Tetrahedron Letters, 1995 , vol. 36, # 50 p. 9085 - 9088
反应条件
1: 92 percent / NaBH4*H2O / acetonitrile; methanol / 1 h / 0 - 5 °C 2: 10 percent / 4 h / 180 °C / 0.5 Torr View Scheme
参考文献
Katritzky, Alan R.; Chermprapai, Amornsri; Patel, Ranjan C.; Tarraga-Tomas, Alberto
Journal of Organic Chemistry, 1982 , vol. 47, # 3 p. 492 - 497
反应条件
1: 94 percent / NaBH4*H2O / acetonitrile; methanol / 1 h / 0 - 5 °C 2: 12 percent / 4 h / 160 °C / 0.5 Torr View Scheme
参考文献
Katritzky, Alan R.; Chermprapai, Amornsri; Patel, Ranjan C.; Tarraga-Tomas, Alberto
Journal of Organic Chemistry, 1982 , vol. 47, # 3 p. 492 - 497
反应条件
1.1: dichloromethane / 0.5 h / 20 °C / |Inert atmosphere 1.2: 0.25 h / 20 °C / |Inert atmosphere 2.1: triethylamine / tetrahydrofuran / 18 h / 0 - 20 °C / |Inert atmosphere 3.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol / 18 h / 100 °C / |Inert atmosphere View Scheme
参考文献
Goggins, Sean; Rosevere, Eleanor; Bellini, Clement; Allen, Joseph C.; Marsh, Barrie J.; Mahon, Mary F.; Frost, Christopher G.
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 1 p. 47 - 52
反应条件
N,N-dimethyl acetamide; zinc; bis(dibenzylideneacetone)-palladium(0) 1.) room temperature, 1 h, 2.) THF, 25 deg C, 14 h; Yield given. Multistep reaction;
参考文献
Prasad, A. S. Bhanu; Stevenson, Thomas M.; Citineni, Janakiram Rao; Nyzam, Valerie; Knochel, Paul
Tetrahedron, 1997 , vol. 53, # 21 p. 7237 - 7254
反应条件
in dimethyl sulfoxide T=20°C; Arylation; 1 h;
参考文献
Gurczynski, Marek; Tomasik, Piotr
Organic Preparations and Procedures International, 1991 , vol. 23, # 4 p. 438 - 441
参考文献
Seto, Masaki; Aramaki, Yoshio; Imoto, Hiroshi; Aikawa, Katsuji; Oda, Tsuneo; Kanzaki, Naoyuki; Iizawa, Yuji; Baba, Masanori; Shiraishi, Mitsuru
Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 7 p. 818 - 829
反应条件
acetic acid; acetyl chloride
参考文献
Forsyth; Pyman
Journal of the Chemical Society, 1926 , p. 2920
Journal of the Chemical Society, 1930 , p. 398
反应条件
Multistep reaction.;
参考文献
Gros, Philippe; Doudouh, Abdelatif; Fort, Yves
Tetrahedron Letters, 2004 , vol. 45, # 33 p. 6239 - 6241
