3,6-二氨基-9-吖啶酮合成路线 （共 13 条）
反应条件
sodium hydroxide; sodium amalgam; water
参考文献
Albert; Linnell
Journal of the Chemical Society, 1936 , p. 88,93
参考文献
Schoepff
Chemische Berichte, 1894 , vol. 27, p. 2318
反应条件
1: Na2CO3 / N,N-dimethyl-acetamide 2: 70 percent / POCl3 3: DIPEA / acetonitrile / 28 h / Heating View Scheme
参考文献
Martins, Cristina; Gunaratnam, Mekala; Stuart, John; Makwana, Vaidahi; Greciano, Olga; Reszka, Anthony P.; Kelland, Lloyd R.; Neidle, Stephen
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 8 p. 2293 - 2298
反应条件
hydrogenchloride; tin(ll) chloride in ethanol
3 h; Heating;
参考文献
ANTISOMA PLC; CANCER RESEARCH TECHNOLOGY LTD
Patent: WO2006/95139 A2, 2006 ;
Location in patent: Figure 1 ;
反应条件
1: 94 percent / CrO3; AcOH
2: 62 percent / SnCl2; hydrochloric acid
View Scheme
参考文献
Martins, Cristina; Gunaratnam, Mekala; Stuart, John; Makwana, Vaidahi; Greciano, Olga; Reszka, Anthony P.; Kelland, Lloyd R.; Neidle, Stephen
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 8 p. 2293 - 2298
反应条件
1: 82 percent / KNO3; H2SO4
2: 94 percent / CrO3; AcOH
3: 62 percent / SnCl2; hydrochloric acid
View Scheme
参考文献
Martins, Cristina; Gunaratnam, Mekala; Stuart, John; Makwana, Vaidahi; Greciano, Olga; Reszka, Anthony P.; Kelland, Lloyd R.; Neidle, Stephen
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 8 p. 2293 - 2298
反应条件
1: potassium carbonate; copper; amyl alcohol / 150 °C
2: H2SO4
3: SnCl2; aqueous HCl
View Scheme
参考文献
Goldberg; Kelly
Journal of the Chemical Society, 1946 , p. 102,107
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
Goldberg; Kelly
Journal of the Chemical Society, 1946 , p. 102,107
参考文献
Goldberg; Kelly
Journal of the Chemical Society, 1946 , p. 102,107
反应条件
1: potassium carbonate; copper; amyl alcohol / 150 °C
2: H2SO4
3: SnCl2; aqueous HCl
View Scheme
参考文献
Goldberg; Kelly
Journal of the Chemical Society, 1946 , p. 102,107
