6-甲基-3-甲基硫代-1,2,4-三嗪合成路线 （共 4 条）
反应条件
in methanol
T=70°C; 4 h;
参考文献
PIERRE FABRE MEDICAMENT; Leroy, Isabelle; Dupont-Passelaigue, Elisabeth; Mialhe, Samuel; Junquero, Didier; Valeille, Karine
Patent: US2013/40928 A1, 2013 ;
Location in patent: Paragraph 0231; 0232; 0233 ;
反应条件
sodium hydrogencarbonate in ethanol; water
T=0 - 20°C; Title compound not separated from byproducts.;
参考文献
Carroll, F. Ivy; Kotturi, Sharadsrikar V.; Navarro, Hernan A.; Mascarella, S. Wayne; Gilmour, Brian P.; Smith, Forrest L.; Gabra, Bichoy H.; Dewey, William L.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 14 p. 3388 - 3391
反应条件
water
T=55 - 60°C; 2 h; Yield given;
参考文献
Bobek, M.; Glowka, M.; Parthasarathy, R.
Journal of Organic Chemistry, 1982 , vol. 47, # 6 p. 913 - 916
反应条件
oxygen; sodium methylate in methanol
48 h; Ambient temperature;
参考文献
Bobek, M.; Glowka, M.; Parthasarathy, R.
Journal of Organic Chemistry, 1982 , vol. 47, # 6 p. 913 - 916
