1: 1.) potassium tert-butoxide / 1.) THF, 0 deg C, 10 min, 2.) THF, 0 deg C, 5 min 2: 70 percent / sodium borohydride / methanol / 0.08 h / 0 °C View Scheme

1: 1.) potassium tert-butoxide / 1.) THF, 0 deg C, 10 min, 2.) THF, 0 deg C, 5 min 2: 70 percent / sodium borohydride / methanol / 0.08 h / 0 °C 3: 100 percent / lithium hydroxide / propan-2-ol; H2O / 1.5 h / Ambient temperature View Scheme

in acetonitrile 36 h; Heating;

1: diethyl ether / 0 °C 2: sodium iodide / acetone / 1 h / Heating 3: 97 percent / acetonitrile / 36 h / Heating View Scheme

1: sodium iodide / acetone / 1 h / Heating 2: 97 percent / acetonitrile / 36 h / Heating View Scheme

1: 1.) potassium tert-butoxide / 1.) THF, 0 deg C, 10 min, 2.) THF, 0 deg C, 5 min 2: 70 percent / sodium borohydride / methanol / 0.08 h / 0 °C View Scheme