N-苄基-2,6-哌啶二酮合成路线 （共 12 条）
反应条件
1: in tetrahydrofuran T=20°C; 0.5 h; 2: With acetic anhydride; triethylamine T=80°C; 1 h;
参考文献
Suarez Del Villar, Irene; Gradillas, Ana; Perez-Castells, Javier
European Journal of Organic Chemistry, 2010 , # 30 p. 5850 - 5862
反应条件
tetra-(n-butyl)ammonium iodide; potassium carbonate in acetone T=20°C;
参考文献
Fuwa, Haruhiko; Kaneko, Akane; Sugimoto, Yasuaki; Tomita, Taisuke; Iwatsubo, Takeshi; Sasaki, Makoto
Heterocycles, 2006 , vol. 70, p. 101 - 106
反应条件
acetyl chloride T=65°C; 10 h; Inert atmosphere;
参考文献
Bisset, Alexander A.; Shiibashi, Akira; Desmond, Jasmine L.; Dishington, Allan; Jones, Teyrnon; Clarkson, Guy J.; Ikariya, Takao; Wills, Martin
Chemical Communications, 2012 , vol. 48, # 98 p. 11978 - 11980
反应条件
dihydridotetrakis(triphenylphosphine)ruthenium(II); sodium hydride; acetonitrile; 1,3-diisopropylimidazolium bromide in toluene 48 h; RefluxInert atmosphereSchlenk techniqueGlovebox;
参考文献
Fu, Zhenqian; Lee, Jeongbin; Kang, Byungjoon; Hong, Soon Hyeok
Organic Letters, 2012 , vol. 14, # 23 p. 6028 - 6031
反应条件
1: benzene / 1 h / Ambient temperature 2: ZnBr2, HMDS / benzene / 2 h / Heating View Scheme
参考文献
Bisset, Alexander A.; Shiibashi, Akira; Desmond, Jasmine L.; Dishington, Allan; Jones, Teyrnon; Clarkson, Guy J.; Ikariya, Takao; Wills, Martin
Chemical Communications, 2012 , vol. 48, # 98 p. 11978 - 11980
反应条件
dihydridotetrakis(triphenylphosphine)ruthenium(II); sodium hydride; acetonitrile; 1,3-diisopropylimidazolium bromide in toluene 24 h; Inert atmosphereReflux;
参考文献
Zhang, Jian; Senthilkumar, Muthaiah; Ghosh, Subhash Chandra; Hong, Soon Hyeok
Angewandte Chemie - International Edition, 2010 , vol. 49, # 36 p. 6391 - 6395
反应条件
1: benzene / 1 h / Ambient temperature 2: ZnBr2, HMDS / benzene / 2 h / Heating View Scheme
参考文献
Bisset, Alexander A.; Shiibashi, Akira; Desmond, Jasmine L.; Dishington, Allan; Jones, Teyrnon; Clarkson, Guy J.; Ikariya, Takao; Wills, Martin
Chemical Communications, 2012 , vol. 48, # 98 p. 11978 - 11980
反应条件
in benzene 12 h; Heating;
参考文献
Aubert, Thierry; Farnier, Michel; Guilard, Roger
Tetrahedron, 1991 , vol. 47, # 1 p. 53 - 60
反应条件
1: CH2Cl2 / Ambient temperature; benzene 2: 62 percent / benzene / 12 h / Heating View Scheme
参考文献
Aubert, Thierry; Farnier, Michel; Guilard, Roger
Tetrahedron, 1991 , vol. 47, # 1 p. 53 - 60
反应条件
1: With lithium triethylborohydride in tetrahydrofuran; toluene T=-70°C; 0.5 h; 2: With 4-(N,N-dimethlyamino)pyridine; N-ethyl-N,N-diisopropylamine; trifluoroacetic anhydride in tetrahydrofuran; toluene T=-70 - 20°C; 2 h;
参考文献
Yu, Jurong; Truc, Vu; Riebel, Peter; Hierl, Elizabeth; Mudryk, Boguslaw
Tetrahedron Letters, 2005 , vol. 46, # 23 p. 4011 - 4013
