1-((4-甲基苯基)甲基)-1H-吡咯-2,5-二酮合成路线 （共 4 条）
反应条件
1: in diethyl ether
T=20°C; 1 h;
2: With sodium acetate; acetic anhydride
T=70°C; 6 h;
参考文献
Puerto Galvis, Carlos E.; Kouznetsov, Vladimir V.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 3 p. 407 - 411
反应条件
1.1: hydroxylamine hydrochloride; sodium carbonate / ethanol / 20 °C
2.1: palladium 10 on activated carbon; hydrogen / ethanol / 20 °C
3.1: diethyl ether / 1 h / 20 °C
3.2: 6 h / 70 °C
View Scheme
参考文献
Puerto Galvis, Carlos E.; Kouznetsov, Vladimir V.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 3 p. 407 - 411
反应条件
1.1: palladium 10 on activated carbon; hydrogen / ethanol / 20 °C
2.1: diethyl ether / 1 h / 20 °C
2.2: 6 h / 70 °C
View Scheme
参考文献
Puerto Galvis, Carlos E.; Kouznetsov, Vladimir V.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 3 p. 407 - 411
反应条件
acetic acid
Yield given;
参考文献
Cechinel Filho; Pinheiro; Nunes; Yunes; Bella Cruz; Moretto
Farmaco, 1994 , vol. 49, # 10 p. 675 - 677
