5-[2-氯-4-(三氟甲基)苯氧基]-2-硝基苯酚合成路线 （共 8 条）
反应条件
in N,N-dimethyl-formamide
参考文献
Rohm and Haas
Patent: CH567359DE2311638 , 1975 ;
Chem.Abstr., 1974 , vol. 80, # 3253
反应条件
tert.-butylhydroperoxide; ammonia in tetrahydrofuran
参考文献
ROHM AND HAAS COMPANY
Patent: EP1013635 A1, 2000 ;
反应条件
potassium carbonate in methanol
1 h; Heating;
参考文献
Schoenowsky; Bieringer
1980 , vol. 35, # 7 p. 902 - 908
反应条件
1: 1.) KOH / 1.) DMSO, H2O, toluene, 2.) 160 deg C, 16 h
2: 88.2 percent / 1 h / 100 °C
3: 50.5 percent / 70percent HNO3, conc. H2SO4 / 1,2-dichloro-ethane / 2 h / 20 °C
4: 97 percent / K2CO3 / methanol / 1 h / Heating
View Scheme
参考文献
Schoenowsky; Bieringer
1980 , vol. 35, # 7 p. 902 - 908
反应条件
1: 88.2 percent / 1 h / 100 °C
2: 50.5 percent / 70percent HNO3, conc. H2SO4 / 1,2-dichloro-ethane / 2 h / 20 °C
3: 97 percent / K2CO3 / methanol / 1 h / Heating
View Scheme
参考文献
Schoenowsky; Bieringer
1980 , vol. 35, # 7 p. 902 - 908
反应条件
1: 50.5 percent / 70percent HNO3, conc. H2SO4 / 1,2-dichloro-ethane / 2 h / 20 °C
2: 97 percent / K2CO3 / methanol / 1 h / Heating
View Scheme
参考文献
Schoenowsky; Bieringer
1980 , vol. 35, # 7 p. 902 - 908
反应条件
1: 1.) KOH / 1.) DMSO, H2O, toluene, 2.) 160 deg C, 16 h
2: 88.2 percent / 1 h / 100 °C
3: 50.5 percent / 70percent HNO3, conc. H2SO4 / 1,2-dichloro-ethane / 2 h / 20 °C
4: 97 percent / K2CO3 / methanol / 1 h / Heating
View Scheme
参考文献
Schoenowsky; Bieringer
1980 , vol. 35, # 7 p. 902 - 908
反应条件
1: (i) KOH, (ii) /BRN= 506456/, sulfolane
2: aq. KOH
View Scheme
参考文献
Rohm and Haas
Patent: CH567359DE2311638 , 1975 ;
Chem.Abstr., 1974 , vol. 80, # 3253
