5-[异氰基[(4-甲基苯基)磺酰基]甲基]-1,3-苯并二氧杂环合成路线 （共 3 条）
反应条件
1: With trichlorophosphate in tetrahydrofuran
T=20°C; 2 h;
2: With 2,6-dimethylpyridine in tetrahydrofuran
T=0 - 20°C; 48 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2004/26863 A1, 2004 ;
Location in patent: Page 49 ;
WO 2004/026863 A1
反应条件
1: POCl3; triethylamine
View Scheme
参考文献
Antuch, Walfrido; Menon, Sanjay; Chen, Quin-Zene; Lu, Yingchun; Sakamuri, Sukumar; Beck, Barbara; Schauer-Vukasinovic, Vesna; Agarwal, Seema; Hess, Sibylle; Doemling, Alexander
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 6 p. 1740 - 1743
反应条件
1: POCl3; triethylamine
View Scheme
参考文献
Antuch, Walfrido; Menon, Sanjay; Chen, Quin-Zene; Lu, Yingchun; Sakamuri, Sukumar; Beck, Barbara; Schauer-Vukasinovic, Vesna; Agarwal, Seema; Hess, Sibylle; Doemling, Alexander
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 6 p. 1740 - 1743
