1-(2-丙炔)-1H-吲哚-2,3-二酮合成路线 （共 3 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide 2 h; Ambient temperature;
参考文献
Singh, Harjinder; Sindhu, Jayant; Khurana, Jitender M.; Sharma, Chetan; Aneja
European Journal of Medicinal Chemistry, 2014 , vol. 77, p. 145 - 154
反应条件
1: indole-2,3-dione With caesium carbonate in N,N-dimethyl-formamide T=16 - 25°C; 1.5 h; 2: propargyl bromide in N,N-dimethyl-formamide T=16 - 25°C;
参考文献
AstraZeneca AB
Patent: US2007/185179 A1, 2007 ;
Location in patent: Page/Page column 5; 9 ;
US 20070185179 A1
反应条件
caesium carbonate in N,N-dimethyl-formamide T=80°C; 0.333333 h; Microwave irradiation;
参考文献
Shanmugam, Ponnusamy; Vaithiyanathan, Vadivel
Canadian Journal of Chemistry, 2009 , vol. 87, # 4 p. 591 - 599
