2-(羟基亚氨基)丙二酸二甲酯合成路线 (共 27 条)
反应条件
1: acetylacetone With sodium acetate; zinc in acetic acid
T=80°C;
2: dimethyl (hydroxyimino)malonate in acetic acid
3 h; Heating;
参考文献
Boiadjiev, Stefan E.; Lightner, David A.
Tetrahedron Asymmetry, 2002 , vol. 13, # 16 p. 1721 - 1732
参考文献
Bouveault; Wahl
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1903 , vol. 137, p. 198
Bulletin de la Societe Chimique de France, 1903 , vol. <3> 29, p. 965
参考文献
Kostyanovskii, R. G.; Mishchenko, A. I.; Prosyanik, A. V.; Zaichenko, N. L.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1983 , vol. 32, p. 1421 - 1428
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1983 , # 7 p. 1572 - 1578
参考文献
Mishchenko,A.I. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1979 , vol. 28, p. 121 - 128
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1979 , vol. 28, p. 131 - 139
反应条件
triethylamine in N,N-dimethyl-formamide
参考文献
Fujisawa Pharmaceutical Co., Ltd.
Patent: US4407798 A1, 1983 ;
反应条件
(i) Na, EtOH, (ii) /BRN= 505934/, acetone; Multistep reaction;
参考文献
Mishchenko,A.I. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1979 , vol. 28, p. 121 - 128
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1979 , vol. 28, p. 131 - 139
反应条件
1: diethyl ether
2: 504 h / 20 °C
View Scheme
参考文献
Mishchenko,A.I. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1979 , vol. 28, p. 121 - 128
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1979 , vol. 28, p. 131 - 139