N-2,3-二氯苯基氨基苯甲酸合成路线 (共 4 条)
反应条件
n-ethyl morpholine; copper diacetate in N,N-dimethyl-formamide T=145°C; Ullmann-Goldberg condensation; 3 h; Inert atmosphere;
参考文献
Dokorou, Vaso; Primikiri, Alexandra; Kovala-Demertzi, Dimitra
Journal of Inorganic Biochemistry, 2011 , vol. 105, # 2 p. 195 - 201
反应条件
4-methyl-morpholine; copper(I) oxide in 1,4-dioxane 16 h; Heating;
参考文献
Chalmers; Scholz; Topliss; Kolliniatis; Munro; Craik; Iskander; Stockigt
Journal of Medicinal Chemistry, 1993 , vol. 36, # 9 p. 1272 - 1277
反应条件
(i) aq. KOH, (ii) /BRN= 472027/, Cu; Multistep reaction;
参考文献
Moffett,R.B.; Aspergren,B.D.
Journal of the American Chemical Society, 1960 , vol. 82, p. 1600 - 1607
反应条件
CaH2; diethylene glycol dimethyl ether; copper(ll) bromide
参考文献
Juby,P.F. et al.
Journal of Medicinal Chemistry, 1968 , vol. 11, # 1 p. 111 - 117