4-(6-甲氧基-1,3-苯并噻唑-2-基)苯胺合成路线 （共 14 条）
参考文献
Tasler, Stefan; Mueller, Oliver; Wieber, Tanja; Herz, Thomas; Pegoraro, Stefano; Saeb, Wael; Lang, Martin; Krauss, Rolf; Totzke, Frank; Zirrgiebel, Ute; Ehlert, Jan E.; Kubbutat, Michael H.G.; Schaechtele, Christoph
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 18 p. 6728 - 6737
反应条件
1: N,N-dimethyl-formamide / 18 h / 140 °C
2: tin(ll) chloride; ethanol / 3 h / |Reflux
View Scheme
参考文献
Pan, Jinhe; Mason, Neale S.; Debnath, Manik L.; Mathis, Chester A.; Klunk, William E.; Lin, Kuo-Shyan
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 6 p. 1720 - 1726
反应条件
1: With sodium methylate in methanol
T=20°C; 4 h;
2: With sodium tetrahydroborate
1.5 h; Reflux;
参考文献
Chi, Dae-Yoon; Lee, Byoung-Se; Uthaiwan, Sirion; Chu, So-Young; Bae, Yu-Jin; Park, Chansoo; Moon, Dae-Hyuk; Ryu, Jin-Sook; Kim, Jae-Seung; Oh, Seung-Jun
Patent: US2012/214994 A1, 2012 ;
Location in patent: Page/Page column 14 ;
反应条件
potassium carbonate in dimethyl sulfoxide
T=100°C; 16 h;
参考文献
UNIVERSITY OF PITTSBURGH
Patent: US2003/236391 A1, 2003 ;
Location in patent: Page 15 - 16 ;
