反应条件
1.1: 88 percent / aspartic acid-derived P-chirogenic diaminophosphine oxide; BSA; iPr2NEt / (η3-C3H5PdCl)2 / 3.5 h / 20 °C 2.1: SmI2 / methanol; tetrahydrofuran / 5 h / 0 - 20 °C 2.2: 87 percent / NEt3 / CH2Cl2 / 0.5 h / 20 °C 3.1: 76 percent / dimethylformamide / 50 °C 4.1: 85 percent / 2nd generation Grubbs catalyst / CH2Cl2 / 3.5 h / Heating 5.1: 72 percent / H2 / Pd/C / ethanol; ethyl acetate View Scheme
参考文献
Nemoto, Tetsuhiro; Jin, Long; Nakamura, Hiroshi; Hamada, Yasumasa
Tetrahedron Letters, 2006 , vol. 47, # 37 p. 6577 - 6581
