2-乙酰基-7-甲氧基苯并呋喃合成路线 （共 14 条）
反应条件
1: ClSO3H / 1,2-dichloro-ethane / -20 - -15 °C
2: Et3N / CH2Cl2 / 27 °C
3: AlCl3 / chlorobenzene / 110 °C
5: NaOH / H2O
View Scheme
参考文献
Ohishi; Mukai; Nagahara; Yajima; Kajikawa
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 9 p. 2398 - 2405
反应条件
nitric acid in acetic anhydride
T=26°C; 1 h;
参考文献
Ando, Kumiko; Tsuji, Eriko; Ando, Yuko; Kuwata, Noriko; Kunitomo, Jun-Ichi; Yamashita, Masayuki; Ohta, Shunsaku; Kohno, Shigekatsu; Ohishi, Yoshitaka
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 4 p. 625 - 635
反应条件
nitric acid in acetic anhydride
T=13 - 15°C; 0.75 h;
参考文献
Bachelet, Jean-Pierre; Clavel, Jean-Marc; Demerseman, Pierre; Royer, Rene
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 737 - 739
反应条件
1: zinc / benzene / Heating
2: P2O5 / toluene / 3 h / Irradiation
3: 40 percent / NBS / CCl4 / 48 h / Heating
4: 55 percent / ammonia (liquid) / tetrahydrofuran / 3 h
5: H2 / Raney nickel / ethanol / 760 Torr / Ambient temperature
View Scheme
参考文献
Berthelot; Vaccher; Flouquet; Luyckx; Brunet; Boulanger; Frippiat; Vercauteren; Debaert; Evrard; Durant
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 4 p. 395 - 402
