2-氨基-1-苄基苯并咪唑合成路线 （共 7 条）
反应条件
potassium hydroxide in ethanol T=20°C;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2009/39321 A1, 2009 ;
Location in patent: Page/Page column 14 ;
WO 2009/039321 A1
反应条件
potassium carbonate; potassium hydroxide in acetone 3 h; Reflux;
参考文献
Di Braccio, Mario; Grossi, Giancarlo; Signorello, Maria Grazia; Leoncini, Giuliana; Cichero, Elena; Fossa, Paola; Alfei, Silvana; Damonte, Gianluca
European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 564 - 578
反应条件
in water T=150°C; 1.25 h;
参考文献
Korbonits, Dezsoe; Kanzel-Szvoboda, Ida; Goenczi, Csaba; Simon, Kalman; Kolonits, Pal
Chemische Berichte, 1989 , vol. 122, p. 1107 - 1112
反应条件
in acetone Addition;
参考文献
Ogunbiyi, O.; Kajbaf, M.; Lamb, J. H.; Jahanshahi, M.; Gorrod, J. W.; Naylor, S.
Toxicology Letters, 1995 , vol. 78, # 1 p. 25 - 34
反应条件
potassium hydroxide in acetone T=20°C;
参考文献
Guida, Xuan; Jianhua, Han; Xiaomin, Li
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 9 p. 1080 - 1083
反应条件
in pyridine 2 h; Heating;
参考文献
Korbonits, Dezsoe; Kanzel-Szvoboda, Ida; Goenczi, Csaba; Simon, Kalman; Kolonits, Pal
Chemische Berichte, 1989 , vol. 122, p. 1107 - 1112
反应条件
1: 65 percent / butan-2-one / 48 h / Heating
2: 87 percent / NaOH / H2O / 40 - 50 °C
View Scheme
参考文献
Da Settimo; Primofiore; Marini
Farmaco, 1992 , vol. 47, # 10 p. 1293 - 1313
