1.1: MeLi; diisopropylamine / tetrahydrofuran / 3 h / 0 °C 1.2: 62 percent / tetrahydrofuran / 2 h / -40 °C 2.1: 95 percent / aq. HCl / tetrahydrofuran / 3 h / 50 °C 3.1: K2CO3 / dimethylformamide / 3 h / 50 °C View Scheme

1.1: MeLi; diisopropylamine / tetrahydrofuran / 3 h / 0 °C 1.2: 62 percent / tetrahydrofuran / 2 h / -40 °C 2.1: 95 percent / aq. HCl / tetrahydrofuran / 3 h / 50 °C View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1.1: t-BuLi / tetrahydrofuran; hexane / 0.33 h / -78 &deg;C<br />1.2: B(OCH₃)3 / tetrahydrofuran; hexane / 2 h / -78 &deg;C<br />1.3: 82 percent / peracetic acid / tetrahydrofuran; acetic acid; H₂O / 1 h / -10 &deg;C<br />2.1: 94 percent / NaH / dimethylformamide / 2 h / 20 &deg;C<br /> <br /> &nbsp;