2,4-二氯-6-甲氧基嘧啶合成路线

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2008/117051 A1, 2008 ;
Location in patent: Page/Page column 29 ;
WO 2008/117051 A1

3764-01-02,4,6-三氯嘧啶

43212-41-52,4-二氯-6-甲氧基嘧啶

参考文献

Buettner
Chemische Berichte, 1903 , vol. 36, p. 2234
Full Text Show Details
Gabriel; Colman
Chemische Berichte, 1903 , vol. 36, p. 3383

3764-01-02,4,6-三氯嘧啶+

124-41-4甲醇钠

43212-41-52,4-二氯-6-甲氧基嘧啶

参考文献

SANOFI; Brollo, Maurice; Carry, Jean-Christophe; Certal, Victor; Didier, Eric; Doerflinger, Gilles; EL Ahmad, Youssef; Filoche-Romme, Bruno; Halley, Frank; Karlsson, Karl Andreas; Schio, Laurent; Thompson, Fabienne
Patent: US2013/274253 A1, 2013 ;
Location in patent: Paragraph 1615-1618 ;

67-56-1甲醇+

3764-01-02,4,6-三氯嘧啶+

124-41-4甲醇钠

43212-41-52,4-二氯-6-甲氧基嘧啶

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2008/135786 A1, 2008 ;
Location in patent: Page/Page column 57-58 ;
WO 2008/135786 A1

67-56-1甲醇+

3764-01-02,4,6-三氯嘧啶

43212-41-52,4-二氯-6-甲氧基嘧啶+

1074-40-44,6-二氯-2-甲氧基嘧啶

参考文献

Kumar, C.H. Vinod; Kavitake, Santosh; Kumar, Sythana Suresh; Cornwall, Philip; Ashok, Mithun; Bhagat, Sagar; Manjunatha, Sulur G.; Nambiar, Sudhir
Organic Process Research and Development, 2012 , vol. 16, # 8 p. 1416 - 1421

43212-41-52,4-二氯-6-甲氧基嘧啶+

124-41-4甲醇钠

6320-15-6

参考文献

Buettner
Chemische Berichte, 1903 , vol. 36, p. 2234

43212-41-52,4-二氯-6-甲氧基嘧啶

5734-64-5

参考文献

Gabriel; Colman
Chemische Berichte, 1903 , vol. 36, p. 3383

43212-41-52,4-二氯-6-甲氧基嘧啶+

7664-41-7氨气

5734-64-5