3'-硝基-4'-苄氧基-2-溴苯乙酮合成路线 （共 16 条）
反应条件
phenyltrimethylammonium tribromide in methanol; dichloromethane T=20°C;
参考文献
Givens, Richard S.; Stensrud, Kenneth; Conrad, Peter G.; Yousef, Abraham L.; Perera, Chamani; Senadheera, Sanjeewa N.; Heger, Dominik; Wirz, Jakob
Canadian Journal of Chemistry, 2011 , vol. 89, # 3 p. 364 - 384
反应条件
1: TBAI, K2CO3 / acetone 2: Br2 / CHCl3 View Scheme
参考文献
Shan, Wen-Jun; Huang, Ling; Zhou, Qi; Jiang, Huai-Lei; Luo, Zong-Hua; Lai, Ke-Fang; Li, Xing-Shu
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 4 p. 1523 - 1526
反应条件
1: HNO3 / acetic acid / 0 °C 2: TBAI, K2CO3 / acetone 3: Br2 / CHCl3 View Scheme
参考文献
Mohan, K. Chandra; Ravikumar, K.; Vittal, T. V. S. K.; Gido, C. K.
Acta Crystallographica, Section C: Crystal Structure Communications, 1994 , vol. 50, # 4 p. 627 - 629
反应条件
1.1: potassium carbonate / water; acetone / 20 °C 1.2: 17 h / Reflux 2.1: bromine / acetic acid / 20 °C View Scheme
参考文献
Huang, Ling; Shan, Wenjun; Zhou, Qi; Xie, Jiaxing; Lai, Kefang; Li, Xingshu
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 1 p. 249 - 253
反应条件
1.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 20 °C 1.2: 3 h / 20 °C / Reflux 2.1: tetra-n-butylammonium tribromide / tetrahydrofuran; methanol / 4 h View Scheme
参考文献
De Koning, Pieter D.; Gladwell, Iain R.; Moses, Ian B.; Panesar, Maninder S.; Pettman, Alan J.; Thomson, Nicholas M.
Organic Process Research and Development, 2011 , vol. 15, # 6 p. 1247 - 1255
反应条件
sodium hydroxide; sodium tetrahydroborate 1.) MeOH; Multistep reaction;
参考文献
Mereyala, Hari Babu; Sambaru, Kalyani
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 1 p. 167 - 169
反应条件
1: 87 percent / BH3*THF / tetrahydrofuran / -20 °C 2: lipase PS Celite-immobilized / various solvent(s) / 72 h / 37 °C 3: K2CO3 / methanol / 2.5 h / 20 °C View Scheme
参考文献
Hett, Robert; Fang, Qun Kevin; Gao, Yun; Hong, Yaping; Butler, Hal T.; Nie, Xiaoyi; Wald, Stephen A.
Tetrahedron Letters, 1997 , vol. 38, # 7 p. 1125 - 1128
反应条件
1: [{(η5-C5Me5)RhCl}2(μ-Cl)2]; sodium formate / water / 2 h / 20 - 40 °C / Inert atmosphere 2: 5 platinum on carbon; dimethylsulfide; hydrogen / tetrahydrofuran / 12 h / 40 °C / 25858.1 Torr 3: acetic anhydride / tetrahydrofuran / 1 h / 10 - 20 °C View Scheme
参考文献
Hett, Robert; Fang, Qun K.; Gao, Yun; Wald, Stephen A.; Senanayake, Chris H.
Organic Process Research and Development, 1998 , vol. 2, # 2 p. 96 - 99
反应条件
oxazaborolidine from cis (1S,2R)-aminoindanol and trimethylboroxine; borane in tetrahydrofuran T=-15°C;
参考文献
Hett, Robert; Fang, Qun Kevin; Gao, Yun; Hong, Yaping; Butler, Hal T.; Nie, Xiaoyi; Wald, Stephen A.
Tetrahedron Letters, 1997 , vol. 38, # 7 p. 1125 - 1128
反应条件
sodium formate; Triton X-100; (R,R)-TsDPEN; [{(η5-C5Me5)RhCl}2(μ-Cl)2] in water T=28°C; 6 h; Title compound not separated from byproducts;
参考文献
Wang, Fei; Liu, Hui; Cun, Linfeng; Zhu, Jin; Deng, Jingen; Jiang, Yaozhong
Journal of Organic Chemistry, 2005 , vol. 70, # 23 p. 9424 - 9429
