3-[(2-氨基苯基)硫代]丙腈合成路线 （共 4 条）
反应条件
tetrabutylammomium bromide
T=105°C; 0.5 h;
参考文献
Ranu, Brindaban C.; Dey, Suvendu S.; Hajra, Alakananda
Tetrahedron, 2003 , vol. 59, # 14 p. 2417 - 2421
反应条件
ATG in N,N-dimethyl-formamide
T=50°C; Michael condensation; Inert atmosphere;
参考文献
Itabashi, Saori; Lu, Rong; Miyakoshi, Tetsuo
Heterocycles, 2011 , vol. 83, # 1 p. 171 - 177
反应条件
1: potassium hydroxide / water; ethylene glycol / 140 °C / Reflux
2: ATG / N,N-dimethyl-formamide / 50 °C / Inert atmosphere
View Scheme
参考文献
Itabashi, Saori; Lu, Rong; Miyakoshi, Tetsuo
Heterocycles, 2011 , vol. 83, # 1 p. 171 - 177
反应条件
1: 77 percent / trifluoroacetic acid / toluene / 72 h / Heating
2: 55 percent / H2O, NaHCO3 / aq. ethanol / 20 h / Heating
View Scheme
参考文献
Walia; Lankin; et al.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 4 p. 1117 - 1119
