1-乙氧基-2,2,2-三氟乙醇合成路线 （共 58 条）
反应条件
lithium aluminium tetrahydride in diethyl ether T=-78°C; 3 h;
参考文献
Lin, Jin-Hong; Xiao, Ji-Chang
European Journal of Organic Chemistry, 2011 , # 24 p. 4536 - 4539
反应条件
potassium hexamethylsilazane in toluene
参考文献
Surya Prakash; Jog, Parag V.; Batamack, Patrice T. D.; Olah, George A.
Science, 2012 , vol. 338, # 6112 p. 1324 - 1327
反应条件
in water-d2 T=25°C; free energy: -0.86 +/- .03 kcal/mol; determined by 1H NMR (calculation from equilibrium conc.); add. of DMAP as catalyst; Thermodynamic data;
参考文献
Fan, Yun-Hua; Haseltine, John
Tetrahedron Letters, 1996 , vol. 37, # 52 p. 9279 - 9282
参考文献
Minnesota Mining and Mfg. Co.
Patent: US2681370 , 1952 ;
参考文献
Petrov,K.A. et al.
Zhurnal Organicheskoi Khimii, 1977 , vol. 13, # 5 p. 943 - 948,866 - 870
反应条件
potassium carbonate T=130°C; 8 h;
参考文献
Gong; Kato; Kimoto
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 1 p. 25 - 28
反应条件
boron trifluoride diethyl etherate T=20°C; 3.5 h;
参考文献
Sanchez-Aris, Marta; Estivill, Carla; Virgili, Albert
Tetrahedron Asymmetry, 2003 , vol. 14, # 20 p. 3129 - 3135
反应条件
1: trifluoroacetaldehyde ethyl hemiacetal With sulfuric acid T=70 - 150°C; 0.133333 h; microwave irradiation; 2: diazoacetic acid ethyl ester in dichloromethane T=20°C; 0.25 h; Further stages.;
参考文献
Landge, Shainaz M.; Borkin, Dmitry A.; Toeroek, Bela
Tetrahedron Letters, 2007 , vol. 48, # 36 p. 6372 - 6376
反应条件
1: T=20°C; 1 h; 2: With pyridine; chloro-trimethyl-silane T=120°C; 23 h;
参考文献
Yanai, Hikaru; Mimura, Hideyuki; Kawada, Kosuke; Taguchi, Takeo
Tetrahedron, 2007 , vol. 63, # 10 p. 2153 - 2160
反应条件
zinc(II) iodide in dichloromethane 10 h; Heating;
参考文献
Kubota, Toshio; Iijima, Masahiro; Tanaka, Tatsuo
Tetrahedron Letters, 1992 , vol. 33, # 10 p. 1351 - 1354
