N-(2-羟丙基)-N'-[3-(三氟甲基)苯基]乙二酰胺合成路线 (共 2 条)
反应条件
in ethanol
1.5 h; Heating / reflux;
参考文献
ASTRAZENECA AB
Patent: WO2009/58076 A1, 2009 ;
Location in patent: Page/Page column 50 ;
WO 2009/058076 A1
反应条件
1: triethylamine / ethyl acetate / 0 - 25 °C / Inert atmosphere
2: ethanol / 0 - 75 °C / Reflux
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参考文献
AstraZeneca AB
Patent: US2011/224229 A1, 2011 ;