sodium hydrogencarbonate in propan-1-ol; water T=20°C; pH=8; 0.0833333 h;

1: valylleucylserine With sodium hydrogencarbonate in propan-1-ol; water T=20°C; 2: 2,3,4,5,6-Pentafluorophenyl isothiocyanate in propan-1-ol; water T=47°C; 1.16667 h;

1: diethyl ether 2: NaHCO3 / H2O; propan-1-ol / 0.08 h / 20 °C / pH 8 View Scheme

1: 4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide / dichloromethane; acetonitrile / 18 h / 20 °C / Inert atmosphere 2: dichloromethane / 0.5 h / 20 °C / Inert atmosphere 3: N-ethyl-N,N-diisopropylamine / acetonitrile / 8 h / 35 °C / Inert atmosphere 4: diethylamine / methanol / 0.75 h / 120 °C / Microwave irradiation View Scheme

ethanol folgend Eindampfen mit Salzsaeure;

aqueous solution of pH 9 anschliessenden Cyclisierung mit wss.HCl;

sodium hydrogencarbonate in propan-1-ol; water T=47°C; 50 h;