2, 3-二氢-6-苯基-咪唑并[2, 1-b]噻唑盐酸盐合成路线 （共 5 条）
反应条件
in tetrahydrofuran T=-78°C; Alkylation; elimination; 1 h;
参考文献
Sisko, Joseph; Kassick, Andrew J.; Shetzline, Steven B.
Organic Letters, 2000 , vol. 2, # 18 p. 2877 - 2880
反应条件
N-(chloromethylene)-N-methylmethanaminium chloride in pyridine; chloroform 24 h;
参考文献
Andreani; Rambaldi; Bonazzi
Farmaco, Edizione Scientifica, 1980 , vol. 35, # 7 p. 573 - 580
反应条件
in ethanol
1 h; Heating;
参考文献
Lantos, Ivan; Gombatz, Kerry; McGuire, Michael; Pridgen, Lendon; Remich, James; Shilcrat, Susan
Journal of Organic Chemistry, 1988 , vol. 53, # 18 p. 4223 - 4227
参考文献
Mazur,I.A. et al.
Pharmaceutical Chemistry Journal, 1969 , # 8 p. 436 - 439
Khimiko-Farmatsevticheskii Zhurnal, 1969 , # 8 p. 11 - 15
反应条件
1.1: -78 °C
1.2: 77 percent / 25 °C
2.1: RaNi
View Scheme
参考文献
Sisko, Joseph; Kassick, Andrew J.; Shetzline, Steven B.
Organic Letters, 2000 , vol. 2, # 18 p. 2877 - 2880
