2,2,2-三氟苯乙酮合成路线 （共 295 条）
反应条件
n-butyllithium in hexane; toluene T=0°C; 16 h;
参考文献
Sokeirik, Yasser Samir; Sato, Kazuyuki; Omote, Masaaki; Ando, Akira; Kumadaki, Itsumaro
Tetrahedron Letters, 2006 , vol. 47, # 16 p. 2821 - 2824
反应条件
PhMe2SiLi; methylmagnesium bromide in tetrahydrofuran; diethyl ether 1.) -78 deg C, 30 min, 2.) 0 deg C, 90 min;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 7 p. 1215 - 1228
反应条件
in tetrachloromethane 48 h; Ambient temperature;
参考文献
Sera, Akira; Iwasaki, Yasuji; Umeda, Michio; Itoh, Kuniaki
Heterocycles, 1991 , vol. 32, # 2 p. 273 - 278
反应条件
potassium tert-butylate in tetrahydrofuran; N,N-dimethyl-formamide T=20°C; 0.333333 h;
参考文献
Jablonski, Lukas; Billard, Thierry; Langlois, Bernard R.
Tetrahedron Letters, 2003 , vol. 44, # 5 p. 1055 - 1057
反应条件
SS-Phos; [RhCl(η2:η2-cycloocta-1,5-diene)]2; sodium hydroxide in water T=80°C; 24 h; Inert atmosphere;
参考文献
White, James R.; Price, Gareth J.; Plucinski, Pawel K.; Frost, Christopher G.
Tetrahedron Letters, 2009 , vol. 50, # 52 p. 7365 - 7368
反应条件
in diethyl ether; hexane
参考文献
Olah,G.A.; Pittman,C.U.
Journal of the American Chemical Society, 1966 , vol. 88, # 14 p. 3310 - 3312
参考文献
Liu, Kwang-Ting; Chang, Shu-Mei; Chen, Hung-I; Chiu, Pao-Feng; Wu, Tseng-Rong
Journal of Organic Chemistry, 1991 , vol. 56, # 3 p. 1315 - 1317
参考文献
Liu, Kwang-Ting; Kuo, Mann-Yan
Tetrahedron Letters, 1985 , vol. 26, # 3 p. 355 - 358
反应条件
α,α,α-trifluorotoluene; 3-chloro-benzenecarboperoxoic acid in chloroform 1 h; Heating;
参考文献
Kitazume, Tomoya; Kataoka, Junichi
Journal of Fluorine Chemistry, 1996 , vol. 80, # 2 p. 157 - 158
反应条件
sodium hydride 1) DMF, H2O, 60 deg C, 30 min, 2) DMF, 80 deg C, 30 min; Yield given. Multistep reaction;
参考文献
Delgado, Antonio; Clardy, Jon
Tetrahedron Letters, 1992 , vol. 33, # 20 p. 2789 - 2790
