2,2,2-三氟苯乙酮合成路线 （共 295 条）
参考文献
ABBOTT GMBH and CO. KG
Patent: WO2006/40179 A1, 2006 ;
Location in patent: Page/Page column 88; 107-108 ;
WO 2006/040179 A1
反应条件
triphenylphosphine in tetrahydrofuran T=80°C; Wittig Olefination; 10 h; Sealed tube;
参考文献
Wang, Fei; Li, Lingchun; Ni, Chuanfa; Hu, Jinbo
Beilstein Journal of Organic Chemistry, 2014 , vol. 10, p. 344 - 351
反应条件
triphenylphosphine in various solvent(s) T=70°C;
参考文献
Burton, Donald J.
Journal of Fluorine Chemistry, 1983 , vol. 23, p. 339 - 358
反应条件
triphenylphosphine in N,N-dimethyl-formamide 2 h; Heating;
参考文献
Bhadury, Pinaki S.; Palit, Meehir; Sharma, Mamta; Raza, Syed K.; Jaiswal, Devendra K.
Journal of Fluorine Chemistry, 2002 , vol. 116, # 1 p. 75 - 80
反应条件
1: 1.) butyllithium / 1.) Et2O, hexane, RT, 30 min, 2.) Et2O, RT, 17 h 2: 63.8 percent / 10percent KOH / methanol / 3 h / 0 °C View Scheme
参考文献
Ohno, Nobuhiro; Fukamiya, Narihiko; Okano, Masayoshi; Tagahara, Kiyoshi; Lee, Kuo-Hsiung
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 8 p. 1489 - 1495
反应条件
aluminium trichloride in dichloromethane T=0°C; 2 h;
参考文献
Fuji, Kaoru; Node, Manabu; Kawabata, Takeo; Fujimoto, Mayumi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 1043 - 1048
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2991 - 2996
反应条件
Titanium(IV) oxide in water Decomposition; Irradiation; Kinetics; Further Variations:Reagentseffect of ultrasound;
参考文献
Physical Chemistry Chemical Physics, , vol. 1, # 19 p. 4663 - 4668
反应条件
sodium hydride 1) DMF, H2O, 60 deg C, 30 min, 2) DMF, 80 deg C, 30 min; Yield given. Multistep reaction;
参考文献
Delgado, Antonio; Clardy, Jon
Tetrahedron Letters, 1992 , vol. 33, # 20 p. 2789 - 2790
反应条件
1: With lead; tetrabutylammomium bromide in dichloromethane T=30 - 40°C; Sonication; 2: With water; silica gel regioselective reaction;
参考文献
Novikov; Khlebnikov; Khistyaev; Magull
Russian Chemical Bulletin, 2008 , vol. 57, # 5 p. 1070 - 1079
