2,2,2-三氟苯乙酮合成路线 （共 295 条）
反应条件
1: 4,4,4-trifluoro-1-(N-methoxy-N-methylamino)-1-methyl-1-(trimethylsiloxyl)-2-butyne With tetrabutyl ammonium fluoride in tetrahydrofuran; diethyl ether T=-15°C; 0.166667 h; 2: 2,2,2-Trifluoro-1-phenyl-ethanone in tetrahydrofuran; diethyl ether T=20°C; 1 h;
参考文献
Jeong, In Howa; Jeon, Sung Lan; Kim, Bum Tae
Tetrahedron Letters, 2003 , vol. 44, # 38 p. 7213 - 7216
反应条件
boron trifluoride diethyl etherate in diethyl ether 15 h; Ambient temperature;
参考文献
Bozhkova, Nina; Heimgartner, Heinz
Helvetica Chimica Acta, 1989 , vol. 72, p. 825 - 837
反应条件
boron trifluoride diethyl etherate; triethylamine Yield given. Multistep reaction;
参考文献
Bozhkova, Nina; Heimgartner, Heinz
Helvetica Chimica Acta, 1989 , vol. 72, p. 825 - 837
反应条件
boron trifluoride diethyl etherate in diethyl ether 24 h; Ambient temperature;
参考文献
Bozhkova, Nina; Heimgartner, Heinz
Helvetica Chimica Acta, 1989 , vol. 72, p. 825 - 837
反应条件
hydrogen in toluene T=20°C; Orito reaction; P=750.075 Torr; optical yield given as percent eeenantioselective reaction;
参考文献
Balazsik, Katalin; Szori, Kornel; Szollosi, Gyoergy; Bartok, Mihaly
Catalysis Communications, 2011 , vol. 12, # 15 p. 1410 - 1414
反应条件
dihydrogen peroxide; iodine monofluoride; bis(acetylacetonate)oxovanadium in water Heating / reflux; Product distribution / selectivity;
参考文献
Honeywell International Inc.
Patent: US7132578 B1, 2006 ;
Location in patent: Page/Page column 6 ;
反应条件
anhydrous magnesium perchlorate; polymer-bound NADH (2a) in acetonitrile; benzene 120 h; Ambient temperature; Further byproducts given;
参考文献
Dupas, G.; Bourguignon, J.; Ruffin, C.; Queguiner, G.
Tetrahedron Letters, 1982 , vol. 23, # 49 p. 5141 - 5144
反应条件
1: 2-monochloropropane With lithium chloride; zinc(II) chloride in tetrahydrofuran T=20°C; 1 h; 2: 2,2,2-Trifluoro-1-phenyl-ethanone in tetrahydrofuran T=0°C; 2 h;
参考文献
Journal of the American Chemical Society, , vol. 128, # 31 p. 9998 - 9999
反应条件
1: iso-propylmagnesium bromide With trimethylsilyl-methylmagnesium chloride; lithium chloride; zinc(II) chloride in tetrahydrofuran; diethyl ether T=20°C; Grignard addition; 2: 2,2,2-Trifluoro-1-phenyl-ethanone in tetrahydrofuran; diethyl ether T=0°C; Grignard addition; 3 h;
参考文献
Chemical Communications, , vol. 46, # 15 p. 2674 - 2676
反应条件
(1R,2R)-N,N,N',N'-tetraethyl-1,2-diphenylethane-1,2-diamine in hexane; toluene T=5°C; 0.5 h;
参考文献
Organic Letters, , vol. 10, # 17 p. 3915 - 3918
