2,2,2-三氟苯乙酮合成路线 （共 295 条）
反应条件
1: With lead; tetrabutylammomium bromide in dichloromethane T=30 - 40°C; Sonication; 2: With water; silica gel regioselective reaction;
参考文献
Novikov; Khlebnikov; Khistyaev; Magull
Russian Chemical Bulletin, 2008 , vol. 57, # 5 p. 1070 - 1079
反应条件
1.1: 52 percent 2.1: 73 percent / NaH / tetrahydrofuran / 20 °C 3.1: O3 / CH2Cl2 / -78 °C 3.2: 54 percent / Me2S / CH2Cl2 / -78 - 20 °C 4.1: NaClO2; KH2PO4; isobutene / 2-methyl-propan-2-ol; H2O / 16 h / 20 °C View Scheme
参考文献
Bravo, Pierfrancesco; Frigerio, Massimo; Resnati, Guiseppe
Journal of Organic Chemistry, 1990 , vol. 55, # 13 p. 4216 - 4218
反应条件
boron trifluoride diethyl etherate; triethylamine Yield given. Multistep reaction;
参考文献
Bozhkova, Nina; Heimgartner, Heinz
Helvetica Chimica Acta, 1989 , vol. 72, p. 825 - 837
反应条件
boron trifluoride diethyl etherate in diethyl ether 24 h; Ambient temperature;
参考文献
Bozhkova, Nina; Heimgartner, Heinz
Helvetica Chimica Acta, 1989 , vol. 72, p. 825 - 837
反应条件
in xylene Heating; Yield given. Yields of byproduct given;
参考文献
Damas, A. Margarida; Gould, Robert O.; Harding, Marjorie M.; Paton, R. Michael; Ross, John F.; Crosby, John
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2991 - 2996
反应条件
1: LiAlH4 / diethyl ether
2: oleum / 0 °C
3: nitric acid / -30 °C
4: acetonitrile / Ambient temperature
View Scheme
参考文献
Jarczewski, Arnold; Schroeder, Grzegorz; Dworniczak, Miroslaw
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1986 , p. 55 - 60
反应条件
ozone in diethyl ether
T=-70°C;
参考文献
Kawamura, Shin-Ichi; Yamakoshi, Hideyuki; Abe, Manabu; Masuyama, Araki; Nojima, Masatomo
Tetrahedron, 2002 , vol. 58, # 5 p. 891 - 896
反应条件
1: 62 percent / conc. H2SO4, dibromoisocyanuric acid / 10 deg C to RT
2: 86 percent / NH2OH*HCl, KOH / propan-2-ol / 48 h / Heating
View Scheme
参考文献
Kogon, Alexander A.; Bochkariov, Dmitry E.; Baskunov, Boris P.; Cheprakov, Andrew V.
Liebigs Annalen der Chemie, 1992 , # 8 p. 879 - 882
反应条件
Irradiation; Quantum yieldMechanism;
参考文献
Wagner, Peter J.; Truman, Royal J.; Scaiano, J. C.
Journal of the American Chemical Society, 1985 , vol. 107, # 24 p. 7093 - 7097
反应条件
NaHCO3 - Na2CO3 buffer in water; isopropyl alcohol
T=50°C; deuterium isotope effect; MechanismRate constant;
参考文献
Chipman, David M.; Yaniv, Ruth; Eikeren, Paul van
Journal of the American Chemical Society, 1980 , vol. 102, # 9 p. 3244 - 3246
