2,2,2-三氟苯乙酮合成路线 （共 295 条）
反应条件
4-(N,N-dimethlyamino)pyridine in dichloromethane 40 h; Ambient temperature;
参考文献
Naumann, Dieter; Finke, Martina; Lange, Horst; Dukat, Wolfgang; Tyrra, Wieland
Journal of Fluorine Chemistry, 1992 , vol. 56, # 2 p. 215 - 237
反应条件
1: NaOMe, triethylene glycol 2: aq. HClO4 / dioxane / 15.9 - 29.9 °C View Scheme
参考文献
Diderich,G.
Helvetica Chimica Acta, 1972 , vol. 55, p. 2103 - 2112
反应条件
1: trifluoroacetic anhydride With AlCl3, aluminium chloride in chloroform T=-10°C; Friedel-Crafts Acylation; 0.0833333 h; 2: phenyltrimethyl silane in chloroform T=-10 - -3°C; Kinetics;
参考文献
Wolf, Richard A.
Organic Process Research and Development, 2008 , vol. 12, # 1 p. 23 - 29
反应条件
oxygen; methylene blue in acetonitrile T=20°C; Irradiation; Yield given. Yields of byproduct given;
参考文献
Nojima, Takayuki; Ishiguro, Katsuya; Sawaki, Yasuhiko
Journal of Organic Chemistry, 1997 , vol. 62, # 20 p. 6911 - 6917
反应条件
in 1,3,5-trimethyl-benzene T=161°C; 4 h;
参考文献
Paton, R. Michael; Robertson, Fiona M.; Ross, John F.; Crosby, John
Journal of the Chemical Society, Chemical Communications, 1980 , # 15 p. 714 - 715
反应条件
in 1-methyl-pyrrolidin-2-one T=20°C; 1.5 h;
参考文献
Kakino; Shimizu; Yamamoto
Bulletin of the Chemical Society of Japan, 2001 , vol. 74, # 2 p. 371 - 376
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C 1.2: 4 h / |Acidic conditions 2.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / ethyl acetate / 13 h / |Reflux View Scheme
参考文献
Cheng, Huicheng; Pei, Yu; Leng, Faqiang; Li, Jingya; Liang, Apeng; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng
Tetrahedron Letters, 2013 , vol. 54, # 33 p. 4483 - 4486
反应条件
in octane; diethyl ether T=-78°C; 0.166667 h; C6H5Li added to ester;
参考文献
Chen, Loomis S.; Chen, Grace. J.; Tamborski, Christ
Journal of Fluorine Chemistry, 1981 , vol. 18, p. 117 - 130
反应条件
in 1,3,5-trimethyl-benzene T=161°C; 4 h;
参考文献
Paton, R. Michael; Robertson, Fiona M.; Ross, John F.; Crosby, John
Journal of the Chemical Society, Chemical Communications, 1980 , # 15 p. 714 - 715
反应条件
in tetrahydrofuran T=-80 - 20°C; 2 h;
参考文献
Yamazaki, Takashi; Terajima, Tsukasa; Kawasaki-Taskasuka, Tomoko
Tetrahedron, 2008 , vol. 64, # 10 p. 2419 - 2424
