2-(2-氰基苯基)苯甲腈合成路线 （共 37 条）
反应条件
manganese; zirconocene dichloride; NiCl2(2,9-dimethyl-1,10-phenanthroline); lithium chloride in ethylene glycol dimethyl ether
T=20°C; 1 h; Inert atmosphere;
参考文献
Peng, Jianbiao; Liu, Xiang; Kishi, Yoshito
Tetrahedron Letters, 2011 , vol. 52, # 17 p. 2172 - 2175
反应条件
pyridine; manganese; FeBr2; cobalt(II) dibromide in acetonitrile
T=50°C; 24 h;
参考文献
Perichon, Jacques; Gosmini, Corinne; Bastienne, Mylene; Gomes, Paulo
Patent: US2004/186328 A1, 2004 ;
Location in patent: Page 13-14 ;
反应条件
amidosulfamic acid in sulfolane
T=180°C; 3 h;
参考文献
Knapp; Keenan; Zhang; Fikar; Potenza; Schugar
Journal of the American Chemical Society, 1990 , vol. 112, # 9 p. 3452 - 3464
反应条件
N-chloro-succinimide; tetrakis(triphenylphosphine) palladium(0) in various solvent(s)
T=35 - 45°C;
参考文献
Hossain, Kabir M.; Kameyama, Toru; Shibata, Takanori; Takagi, Kentaro
Bulletin of the Chemical Society of Japan, 2001 , vol. 74, # 12 p. 2415 - 2420
反应条件
bromobenzene; zinc dibromide; zinc; acetic acid; cobalt(II) dibromide in acetonitrile
T=20°C; 3 h;
参考文献
Perichon, Jacques; Gosmini, Corinne; Bastienne, Mylene; Gomes, Paulo
Patent: US2004/186328 A1, 2004 ;
Location in patent: Page 12-13 ;
反应条件
trichlorophosphate in pyridine
参考文献
Ortho Pharmaceutical Corporation
Patent: US5256658 A1, 1993 ;
US 5256658 A
反应条件
1: With iso-propylmagnesium bromide in tetrahydrofuran
T=-40°C; 0.5 h;
2: With 1,2-di-iodoethane; iron(III) chloride in tetrahydrofuran
T=-40°C; 2 h;
参考文献
Cahiez, Gerard; Chaboche, Christophe; Mahuteau-Betzer, Florence; Ahr, Mathieu
Organic Letters, 2005 , vol. 7, # 10 p. 1943 - 1946
反应条件
manganese; cobalt (II) bromide; triphenylphosphine; trifluoroacetic acid in pyridine; N,N-dimethyl-formamide
T=50°C;
参考文献
Amatore, Muriel; Gosmini, Corinne
Angewandte Chemie - International Edition, 2008 , vol. 47, # 11 p. 2089 - 2092
反应条件
manganese; cobalt (II) bromide; triphenylphosphine; trifluoroacetic acid in pyridine; N,N-dimethyl-formamide
T=50°C;
参考文献
Amatore, Muriel; Gosmini, Corinne
Angewandte Chemie - International Edition, 2008 , vol. 47, # 11 p. 2089 - 2092
反应条件
oxygen; lithium chloride; manganese (II) chloride in tetrahydrofuran
T=-5 - 0°C; Inert atmosphere;
参考文献
Cahiez, Gerard; Duplais, Christophe; Buendia, Julien
Angewandte Chemie, International Edition, 2009 , vol. 48, # 36 p. 6731 - 6734
