5-氨基-1-苄基-1H-1,2,3-噻唑-4-羧胺合成路线 （共 18 条）
反应条件
1: 2-cyano-acetamide With potassium hydroxide in ethanol 0.25 h; 2: benzyl azide in ethanol 1 h; Heating;
参考文献
Kislyi; Danilova; Semenov
Russian Chemical Bulletin, 2003 , vol. 52, # 8 p. 1770 - 1776
反应条件
ammonia; ethylene glycol
参考文献
Journal of the American Chemical Society, , vol. 78, p. 5832,5835
反应条件
1.1: sodium azide; N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 4 h / 25 °C 2.1: sodium hydroxide / water; dimethyl sulfoxide / 0.25 h / 25 °C 2.2: 25 °C View Scheme
反应条件
formamide T=190°C; 1 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2344 - 2351
反应条件
1: 75 percent / 2M-sodium hydroxide, hydrogen peroxide / ethanol / 1 h / 65 °C 2: formamide / 1 h / 190 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2344 - 2351
反应条件
1: 95 percent / sodium hydroxide / ethanol / 0.25 h / Heating 2: 75 percent / 2M-sodium hydroxide, hydrogen peroxide / ethanol / 1 h / 65 °C 3: formamide / 1 h / 190 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2344 - 2351
反应条件
1: 80 percent / potassium carbonate / dimethylformamide / 24 h / 23 °C 2: 95 percent / sodium hydroxide / ethanol / 0.25 h / Heating 3: 75 percent / 2M-sodium hydroxide, hydrogen peroxide / ethanol / 1 h / 65 °C 4: formamide / 1 h / 190 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2344 - 2351
反应条件
1: cold 1N-sodium hydroxide 2: formamide / 1 h / 190 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2344 - 2351
反应条件
benzenesulphonyl azide; sodium ethanolate 1) EtOH, 5 min, 2) 1 h, r.t.; Yield given. Multistep reaction;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 27, # 6 p. 607 - 613
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 27, # 6 p. 775 - 782
反应条件
1: 15 percent / sodium ethoxide / 1 h / Heating 2: cold 1N-potassium hydroxide 3: formamide / 1 h / 190 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2344 - 2351
